Purpose: The treatment of comminuted fractures of distal humerus poses a challenge for orthopaedics. Previous studies assessing the global stiffness of the bone - stabilizer system - made it impossible to explicitly indicate an optimal configuration of the locking plates in the treatment of this kind of fractures. The aim of the present research was to comparatively analyze the stabilization conditions of intraarticular fractures of distal humerus with the use of various configurations of the stabilizer.
Methods: The research was based on the analysis of mutual displacements of bone fragments. Such evaluation was performed with the use of numerical simulation conducted with the use of the finite element method. A realistic model of humerus was based on the CT data. Three spatial configurations of the stabilizer (parallel, posteromedial and posterolateral) were considered. The mutual displacements of bone fragments as well as the deformity of the stabilizer under various loading conditions were analyzed.
Results: In most cases, the parallel setting of the plates ensures a better stabilization of the bone fragments than the perpendicular configuration. The most difficult conditions of stabilization were obtained for the lateral bone fragment. The value of the fragments' displacements significantly increases for loading directions occurring with ascending flexion angle of the joint.
Conclusions: In most cases, the parallel setting of the plates ensures a better stabilization of the bone fragments than the perpendicular configuration.
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Pharmaceutics
December 2024
Post-Graduate Program in Dentistry, School of Health and Life Sciences, Pontifical Catholic University of Rio Grande do Sul (PUCRS), Porto Alegre 90619-900, RS, Brazil.
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Department of Applied Biology, Faculty of Textile Science and Technology, Shinshu University, Ueda 386-8567, Nagano, Japan.
Osteocalcin is a useful biomarker for bone formation and bone-related diseases. KTM219 is an anti-osteocalcin C-terminal peptide antibody. The single-chain variable region (scFv) and antigen-binding fragment (Fab) of KTM219 are applicable to the Quenchbody (Q-body) immunoassay.
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Australian Centre for Ancient DNA, The Environment Institute, School of Biological Sciences, The University of Adelaide, Adelaide, SA 5000, Australia.
Unlabelled: In many human rights and criminal contexts, skeletal remains are often the only available samples, and they present a significant challenge for forensic DNA profiling due to DNA degradation. Ancient DNA methods, particularly capture hybridization enrichment, have been proposed for dealing with severely degraded bones, given their capacity to yield results in ancient remains.
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1Department of biology, College of Education for Women, University of Kirkuk, Iraq.
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Department of Biomedical and NeuroMotor Sciences (DIBINEM), University of Bologna, 40126 Bologna, Italy.
Background/objectives: Mummy studies allow to reconstruct the characteristic of a population in a specific spatiotemporal context, in terms of living conditions, pathologies and death. Radiology represents an efficient diagnostic technique able to establish the preservation state of mummified organs and to estimate the patient's pathological conditions. However, the radiological approach shows some limitations.
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