The American College of Obstetricians and Gynecologists (ACOG) recommends that oral contraceptives (OC) should be available over the counter (OTC). This study explored women's attitudes toward OC OTC in rural South Carolina. In-depth, individual interviews were conducted with 52 women ages 18-44 years old. Data analysis was informed by a reproductive justice theoretical framework and included an inductive, constant-comparative approach using HyperRESEARCH 3.7.5. Participants self-identified as either Black (62%) or White (28%). Participants believed that OC OTC would prevent unintended pregnancy by improving anonymity, convenience, and access to contraception. Many participants faced barriers to receiving a prescription, including time, transportation, cost, stigma, embarrassment, and clinician refusal based on religious reasons. Participants believed OC OTC would improve women's control over their fertility and emphasized the importance of health insurance coverage for OC OTC. Some participants expressed concerns about the risk of side effects, contraindications, and the potential for abuse. Some participants believed women, especially adolescents, required physician guidance and an annual exam to use OC. Findings suggest that a lack of knowledge and misinformation about the risks of OC serve as a barrier among some women in rural areas. Widespread acceptance of OC OTC will require messaging strategies to dispel safety concerns about OC OTC and empower women.
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http://dx.doi.org/10.1080/10810730.2020.1752334 | DOI Listing |
JAMA Netw Open
December 2024
School of Pharmacy, University of Maryland, Baltimore.
Importance: Initiating effective therapy early is associated with improved survival among patients hospitalized with gram-negative bloodstream infections; furthermore, providing early phenotype-desirable antimicrobial therapy (PDAT; defined as receipt of a β-lactam antibiotic with the narrowest spectrum of activity to effectively treat the pathogen's phenotype) is crucial for antimicrobial stewardship. However, the timing of targeted therapy among patients hospitalized with gram-negative bloodstream infections is not well understood.
Objective: To compare the clinical outcomes between patients who were hospitalized with Enterobacterales bloodstream infections receiving early vs delayed PDAT.
Planta
December 2024
Federal Scientific Center of the East Asia Terrestrial Biodiversity of the Russian Academy of Sciences Far Eastern Branch, FGBUN FNC Bioraznoobrazia Nazemnoj Bioty Vostocnoj Azii Dal'nevostocnogo Otdelenia Rossijskoj Akademii Nauk, Vladivostok, 690022, Russia.
Long-term cultured calli may experience a biosynthetic shift due to the IAA-dependent expression of the rolA gene, which also affects ROS metabolism. The "hairy root" syndrome is caused by the root-inducing Ri-plasmid of Rhizobium rhizogenes, also known as Agrobacterium rhizogenes. The Ri-plasmid contains genes known as rol genes or root oncogenic loci, which promote root development.
View Article and Find Full Text PDFEur Spine J
December 2024
Division of Spine Surgery, Department of Orthopaedics, University of Maryland Medical Center, 110 South Paca Street, Suite 300, Baltimore, MD, 21201, USA.
Purpose: Three-column osteotomies (3COs), such as pedicle subtraction osteotomy (PSO) and vertebral column resection (VCR), are used to surgically correct rigid adult spinal deformity (ASD). While extensive research exists about complications associated with 3COs, there remains a paucity of studies analyzing risk factors for mortality following 3CO. We believe the mortality rate after 3-column osteotomy will be low with specific identifiable demographic or medical risk factors.
View Article and Find Full Text PDFAngew Chem Int Ed Engl
December 2024
Stellenbosch University Department of Chemistry and Polymer science, Chemistry and Polymer Science, SOUTH AFRICA.
Ethylene glycol or one of its oxidation products are believed to serve as reducing agents in the shape-controlled synthesis of Ag nanocubes (NCs) by the polyol process. The identity of end-groups of polyvinylpyrrolidone (PVP) impacts shape control with alcohol and aldehyde moieties serving as a primary Ag reducing agent. We explored the role of PVP end-groups in the polyol process by measuring the dependence of particle number density of Ag NCs produced on the initial concentration(s) of Ag and PVP using small angle x-ray scattering and statistically large particle size distributions analyzed by scanning electron microscopy.
View Article and Find Full Text PDFBr J Dev Psychol
December 2024
University of Exeter, Exeter, UK.
Misinformation poses a significant threat to modern society. Children and adolescents, highly active on social media, are particularly vulnerable to encountering misinformation from peers. Assessing whether intentionality impacts moral evaluations of misinformers, considering age and group norms, is crucial.
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