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| http://dx.doi.org/10.1016/j.jaad.2020.04.047 | DOI Listing |
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Tissue gliding and mobility are paramount to the success of penile procedures. While postoperative healing is intended to protect, repair, and nourish injured tissues, an overzealous response often leaves painful and debilitating tethering between the corpora, including nerves, and surrounding tissues. This tethering interferes with the intended outcomes of surgery by preventing necessary gliding.
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Sepsis is a potential fetal organ destruction brought on through an overzealous immunologic reaction to infection, causing severe inflammation, septic shock, and damage to different organs. Although there has been progress in the identification and controlling of clinical sepsis, the fatality rates are still significant. This study, for the first time, intended to examine the possible ameliorative impact of Nebivolol, a β1-adrenergic antagonist antihypertensive drug, against nephrotoxicity resulted from cecal ligation and puncture (CLP)-induced sepsis in rats, on molecular basis.
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Columbia University Medical Center, New York City, NY, USA.
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