AI Article Synopsis
- A new method for hydroaminative cyclization of enynes is introduced using specific rhodium catalysts.
- This process involves reacting 2-vinylphenylacetylene compounds with secondary amines to produce 2-aminoindenes effectively.
- The mechanism suggests that the reaction forms carbon-carbon bonds via an aminocarbene ligand generated during the catalysis.
Article Abstract
We report a hydroaminative cyclization of enynes using phosphine-quinolinolato rhodium catalysts. The hydroaminative cyclization of 2-vinylphenylacetylene derivatives with secondary amines gives 2-aminoindenes in good yields. The reaction is considered to proceed through carbon-carbon bond formation on a catalytically generated aminocarbene ligand.
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