Limbic encephalitis in a neuroscientist: CASPR 2 antibody-associated disease after antigen exposure.

J Neuroimmunol

Division of Neurology, Department of Clinical Sciences Lund, Lund University, Skane University Hospital, SE-221 85 Lund, Sweden.

Published: June 2020

Autoimmune limbic encephalitis is part of CASPR 2 antibody-associated disease. A man with this rare disorder and a very high antibody titre had a unique history of laboratory exposure to the antigen. Together with earlier observations this case calls for caution in laboratory handling of nerve tissue.

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http://dx.doi.org/10.1016/j.jneuroim.2020.577231DOI Listing

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