AI Article Synopsis

  • The study analyzed outcomes of patients with prior pelvic surgery or radiation who underwent robot-assisted radical cystectomy (RARC) from 2005-2018.
  • Patients were categorized into three complexity grades based on their surgical history, with higher grades reflecting more extensive previous surgeries or radiation.
  • Results showed that higher complexity groups (grades 2 and 3) experienced more complications within 90 days post-surgery, but there was no increase in readmission rates among these patients.

Article Abstract

Objective: To report the outcomes of patients who underwent robot-assisted radical cystectomy (RARC) and have a history of previous pelvic surgery and/or radiation.

Methods: Retrospective review of our prospectively maintained database between 2005 and 2018. Patients were divided into 3 groups based on surgical complexity; Complexity grade 1 included patients who did not have any history of prior pelvic surgery or radiation (n = 323); Complexity grade 2 included those who had history of a single pelvic surgery or radiation (n = 186); and Complexity grade 3 included those who had history of 2 or more pelvic surgeries, or one or more pelvic surgery and radiation (n = 80). All groups were compared in terms of perioperative outcomes. Multivariate linear and logistic regression models were used to depict the predictors of operative time, ≥500 ml blood loss, 90-day complications, high grade complications, and readmissions.

Results: Complexity grades 2 and 3 exhibited higher 90-day complications compared to CG1 (CG3: 74%, CG1: 59%, CG2: 68%, P = .02), and high grade complications (CG3: 24%, CG1: 13%, CG2 18%, P = .03). On multivariate linear and logistic regression models, CG 3 was significantly associated with higher 90-day complications (OR 2.18, 95% CI 1.21-3.94, P <.01) but not significantly associated with higher rates of significant blood loss, longer operative time, 90-day high grade complications and readmissions.

Conclusion: Patients with higher complexity of the surgical field exhibited more complications after robot-assisted radical cystectomy, but not readmissions.

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Source
http://dx.doi.org/10.1016/j.urology.2020.03.033DOI Listing

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