Objectives: To assess, objectively to determine the deterioration of the photostimulable phosphor plates (PSPs) after several acquisitions.
Methods: Two new PSPs without preliminary use were exposed with an intraoral X-ray unit, and the EXPRESS (Instrumentarium Imaging, Tuusula, Finland) unit was used for scanning of the PSPs. A 12-stepwedge aluminum scale were used superimposed with the PSPs during the X-rays exposures to perform the objective analyses. Objective analysis was carried out by mean gray values using the Image J software through a region of interest (ROI) of 0.1 × 0.1 mm, and the data were analyzed statistically using ANOVA.
Results: For each, the Express PSP a total of 1800 images were acquired during 60 days. The objective analysis showed loss of the mean gray values between the initial and final images. Besides, the percentage of mean gray values' loss was between 0.7%, for the thickest step, and 8.4%, for the lowest thickness step.
Conclusion: After many X-ray exposures of the Express PSP a singular deterioration in the mean gray values could be observed.
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http://dx.doi.org/10.1259/dmfr.20190500 | DOI Listing |
Alzheimers Res Ther
December 2024
University of Pompeu Fabra (UPF), Barcelona, Spain.
Background: Cerebrospinal fluid (CSF) biomarkers of synaptic dysfunction, neuroinflammation, and glial response, complementing Alzheimer's disease (AD) core biomarkers, have improved the pathophysiological characterization of the disease. Here, we tested the hypothesis that the co-expression of multiple CSF biomarkers will help the identification of AD-like phenotypes when biomarker positivity thresholds are not met yet.
Methods: Two hundred and seventy cognitively unimpaired adults with family history (FH) of sporadic AD (mean age = 60.
AJNR Am J Neuroradiol
December 2024
From the Department of Diagnostic Medicine, Dell Medical School at The University of Texas at Austin, Austin, TX, USA (C.Y.H.), Department of Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, IN, USA (N.S., G.A., Q.W., P.C., M.A., J.G.P., B.R.G., P.R.T., G.D.H.), Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, USA (E.C., P.R.T., S.A.P.), Stark Neuroscience Research Institute, Indiana University School of Medicine, Indianapolis, IN, USA (P.R.T., S.A.P.), and the Department of Radiology at Texas Children's Hospital, Houston, TX, USA (S.F.K.).
Background And Purpose: There are multiple MRI perfusion techniques, with limited available literature comparing these techniques in the grading of pediatric brain tumors. For efficiency and limiting scan time, ideally only one MRI perfusion technique can be used in initial imaging. We compared DSC, DCE, and IVIM along with ADC from DWI for differentiating high versus low grade pediatric brain tumors.
View Article and Find Full Text PDFNeurol Neuroimmunol Neuroinflamm
January 2025
From the Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin Ultrahigh Field Facility (B.U.F.F.); Experimental and Clinical Research Center, Charité - Universitätsmedizin Berlin, Germany; Division of Paediatric Neurology, Department of Paediatrics I, Medical University of Innsbruck, Austria; Department of Pediatric Neurology, Olgahospital/Klinikum Stuttgart; Department of Paediatric Neurology, Children's Hospital Datteln, Witten/Herdecke University and Department of Neurology, Charité - Universitätsmedizin Berlin, Germany.
Background And Objectives: Pediatric patients with acute disseminated encephalomyelitis (ADEM) are at risk of impaired brain growth, with long-term neuropsychiatric consequences. We previously reported transient expansions of cerebral ventricle volume (VV) in experimental autoimmune encephalomyelitis, which subsequently normalized. In this study, we investigated changes in VV in ADEM in relation to other brain structures and clinical outcomes.
View Article and Find Full Text PDFWe developed a new sodium magnetic resonance fingerprinting ($^\text{23}\text{Na}$ MRF) method for the simultaneous mapping of $\text{T}_\text{1}$, $\text{T}_\text{2,long}^{*}$, $\text{T}_\text{2,short}^{*}$ and sodium density with built-in $\Delta\text{B}_{1}^{+}$ (radiofrequency transmission inhomogeneities) and $\Delta\text{f}_\text{0}$ corrections (frequency offsets). We based our $^\text{23}\text{Na}$ MRF implementation on a 3D FLORET sequence with 23 radiofrequency pulses. To capture the complex spin ${\frac{\text{3}}{\text{2}}}$ dynamics of the $^\text{23}\text{Na}$ nucleus, the fingerprint dictionary was simulated using the irreducible spherical tensor operators formalism.
View Article and Find Full Text PDFBackground: The increasing clinical use of combining structural MRI (sMRI) with General Movements Assessment (GMA) or Hammersmith Infant Neurological Exam (HINE) before five months corrected age (CA) for early diagnosis of cerebral palsy (CP) lacks sufficient prognostic data for children with CP, especially those with Gross Motor Function Classification System (GMFCS) I.
Objective: Evaluate the predictive value of sMRI, GMA, and HINE individually and in combination for early CP diagnosis and assess accuracy across varying GMFCS levels in a regional cohort of preterm infants.
Methods: We performed sMRI between 39-44 weeks postmenstrual age and GMA and HINE between 12-18 weeks CA in 395 preterm infants born at ≤32 weeks' gestation across five NICUs in Greater Cincinnati.
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