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A brown recluse spider bite wound: a case report and literature review.
J Wound Care
July 2024
University of Toledo, College of Medicine and Life Sciences, Department of Surgery, Toledo, Ohio, US.
The authors have no conflicts of interest.
View Article and Find Full Text PDFUtilization of dapsone and hemoglobin in the epithelial skin regeneration therapy of cutaneous loxoscelism: A case report and integrative literature review.
Sao Paulo Med J
March 2024
MD. Physician, Medical staff, emergency department, general hospital de Pachuca. Pachuca, Hidalgo, Mexico.
Background: Loxosceles spp are arthropods found worldwide. Its bite may produce cutaneous loxoscelism (necrotic or edematous) or cutaneous-visceral loxoscelism. Depending on their severity and location, cutaneous forms are managed with local cold application and systemic administration of antihistamines, corticosteroids, antibiotics, polymorphonuclear inhibitors, and analgesics.
View Article and Find Full Text PDFRole of ErbB and IL-1 signaling pathways in the dermonecrotic lesion induced by Loxosceles sphingomyelinases D.
Arch Toxicol
December 2023
Immunochemistry Laboratory, Butantan Institute, São Paulo, Brazil.
Sphingomyelinase D (SMase D), the main toxic component of Loxosceles venom, has a well-documented role on dermonecrotic lesion triggered by envenomation with these species; however, the intracellular mechanisms involved in this event are still poorly known. Through differential transcriptomics of human keratinocytes treated with L. laeta or L.
View Article and Find Full Text PDFIdentification of a common epitope in knottins and phospholipases D present in Loxosceles sp venom by a monoclonal antibody.
Int J Biol Macromol
August 2023
Universidade Federal do Paraná, Departamento de Patologia Básica, Laboratório de Imunoquímica, Curitiba, PR, Brazil.
In the Americas and specially in Brazil, the Loxosceles intermedia, Loxosceles gaucho and Loxosceles laeta are the three most medically relevant brown spider species, and whose bites can lead to the condition known as loxoscelism. Here, we report the development of a tool capable of identifying a common epitope amongst Loxosceles sp. venom's toxins.
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