Background: The objective of this study was to determine a safe blood sample collection site for clinical investigations, in patients with an intravenous line, which would minimize distress to the patient and provide accurate blood data.
Methods: An intravenous line was established in the left upper limb for administration of Solita T3G (84 mL/h). After 5 min of infusion, two nurses simultaneously collected venous blood samples (vacuum blood collection method) from a site on dorsum of the left hand located 15 cm distal to the site of fluid infusion (the peripheral side), and the cubital fossa of the contralateral upper limb (the opposite side). The results obtained from the blood samples of the contralateral side served as the standard reference. Testing of 41 blood-cell tests and biochemical parameters were outsourced to a specialized company. Between-group differences in test results for the two locations were assessed using the paired -test, with a significance level of < 5%.
Results: No significant differences in mean values (± standard deviation) of blood parameters were observed between the distal site and the contralateral side.
Conclusion: Blood samples collected from a venous site located 15 cm distal to the fluid-infusion site did not show any effect of fluid infusion on the results.
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http://dx.doi.org/10.14740/jh318e | DOI Listing |
Crit Care
January 2025
Department of Cardiology, Aarhus University Hospital, Palle Juul-Jensens Boulevard 99, 8200, Aarhus N, Denmark.
Background: Low-volume hypertonic solutions, such as half-molar lactate (LAC), may be a potential treatment used for fluid resuscitation. This study aimed to evaluate the underlying cardiovascular effects and mechanisms of LAC infusion compared to sodium-matched hypertonic sodium chloride (SAL).
Methods: Eight healthy male participants were randomized in a controlled, single-blinded, crossover study.
J Oral Maxillofac Surg
December 2024
Professor, Private Practice, Proimtech A.Ş., Istanbul, Turkey.
Background: Postoperative nausea and vomiting (PONV) after orthognathic surgery remains one of the most common side effects despite the use of several medications.
Purpose: The study aimed to compare the frequencies of PONV between a combination of metoclopramide with granisetron and granisetron alone.
Study Design, Setting, Sample: A randomized double-blind clinical trial was conducted in 66 consecutive patients who underwent orthognathic surgery at the Department of Oral and Maxillofacial Surgery at Bezmialem Vakif University.
JCO Glob Oncol
January 2025
Division of Medical Oncology, Department of Medicine, Faculty of Medicine Siriraj Hospital, Bangkok, Thailand.
Purpose: The use of short hydration (SH) to prevent cisplatin-induced nephrotoxicity lacks substantive prospective evaluation. The aim of this study was to evaluate the safety and efficacy of SH, including those with head and neck cancer (HNC) who are at higher risks of mucositis that causes diminished oral intake.
Methods: This phase II randomized noncomparative trial included patients with cancer who were scheduled to receive high-dose cisplatin (≥60 mg/m) in combination with another chemotherapy or concurrently with radiotherapy.
Ann Ital Chir
January 2025
Operating Room, Zhongnan Hospital of Wuhan University, 430071 Wuhan, Hubei, China.
Aim: Colorectal cancer (CRC) is one of the most prevalent malignancies, which is commonly treated with curative surgical resection, often leading to intraoperative hypothermia. Therefore, this study aimed to compare and analyze the risk factors for intraoperative hypothermia associated with laparoscopic and open CRC resections under general anesthesia.
Methods: This study included 120 CRC patients admitted between January 2023 and January 2024.
Introduction: Angiotensin II may reduce muscle ischemia during intermittent hemodialysis and thereby decrease the incidence and/or intensity of intradialytic muscle cramps. We aimed to test whether angiotensin II infusion during intermittent hemodialysis is safe, feasible, and effective in the attenuation of muscle cramps.
Methods: We performed a pilot, single-blinded, randomized crossover trial of patients receiving intermittent hemodialysis who frequently experience intradialytic muscle cramps.
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