Sensitive fluorescence detection of atorvastatin by doped carbon dots synthesized in deep eutectic media.

Spectrochim Acta A Mol Biomol Spectrosc

Department of Chemistry, Faculty of Science, Ilam University, Ilam, Iran. Electronic address:

Published: August 2020

Fluorescence properties of nanoparticles can be influenced by solvent. In this work, carbon dots (CDs) were synthesized in deep eutectic solvent by microwave assisted method. Quantum yield (QY) and size of the synthesized CDs were 41.3% and 2 nm, respectively. N/Cl -doped CDs had excellent sensitivity and selectivity for atorvastatin and detection limit was 0.8 nM. Simple and low-cost synthesis method and excellent sensitivity are advantages of this detection method for atorvastatin. The as-synthesized N/Cl-doped CDs were successfully used to determine atorvastatin in blood serum.

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http://dx.doi.org/10.1016/j.saa.2020.118341DOI Listing

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