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Bronchial Challenge in the Diagnosis of Cannabis Allergy.
Curr Allergy Asthma Rep
December 2024
Laboratorios INMUNOTEK, Madrid, Spain.
We have read with great interest the recent review published by Dr. Ebo and collaborators on cannabis allergy. It highlights the difficulties in getting a valid diagnosis because some patients do not admit its consumption, which may not be legalized, there are no commercial extracts and there are problems in cutaneous tests interpretation due to cross-reactivity with other related allergens.
View Article and Find Full Text PDFCannabis sativa as a clinically relevant nsLTP allergen in the Mediterranean region: a case series exemplifying different possible routes of sensitization.
Eur Ann Allergy Clin Immunol
November 2024
Department of Clinical and Experimental Medicine, School and Operative Unit of Allergy and Clinical Immunology, University of Messina, Messina, Italy.
Cannabis is the most widely used drug worldwide sought for recreational and medicinal purposes. Cannabis allergy was first described 50 years ago but has become more frequently reported over the past decade due to a larger industrial and domestic cultivation, and an evolving legal status. However, it remains an infrequent cause of allergy in the Mediterranean European countries.
View Article and Find Full Text PDFEffects of protein variations by different extraction and dehydration approaches on hempseed protein isolate: Protein pattern, amino acid profiling and label-free proteomics.
Food Chem
December 2024
Food Science, School of Chemical Sciences, The University of Auckland, Auckland, 1010, New Zealand; Riddet Institute, Centre of Research Excellence for Food Research, Palmerston North 4474, New Zealand. Electronic address:
This study evaluates the effects of alkaline and micellisation extraction methods, alongside freeze-drying and spray-drying, on the protein subunits, amino acid profiles, and proteome data of hempseed protein isolate (HPI). Findings revealed that the extraction methods affect protein profiles more than the drying methods. Micellisation-extracted HPI showed higher albumin, oleosin, and sulphur-containing protein levels than alkaline-extracted HPI.
View Article and Find Full Text PDFThe Diagnosis of Allergy to Lipid Transfer Proteins.
Curr Allergy Asthma Rep
September 2024
Department of Allergy & Clinical Immunology, Royal Brompton & Harefield Hospitals, part of Guys and St Thomas NHS Foundation Trust, Sydney Street, London, SW3 6NP, UK.
Purpose Of Review: To provide an update on the diagnosis of non-specific Lipid Transfer Protein (nsLTP) allergy.
Recent Findings: More publications report the presence of nsLTP allergy in Northern European countries and nsLTP sensitisation in children. Individuals are more likely to have severe reactions if there is recognition of increasing numbers of LTP components.
IgE-Mediated Cannabis Allergy and Cross-Reactivity Syndromes: A Roadmap for Correct Diagnosis and Management.
Curr Allergy Asthma Rep
August 2024
Department of Paediatrics and the Infla-Med Centre of Excellence, Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp, Belgium.
Article Synopsis
- Increased access and decriminalization of cannabis has led to more reported cases of IgE-dependent cannabis allergy (CA) and related food allergies, but the true prevalence is likely underestimated due to a lack of awareness among healthcare professionals.
- The main symptoms of CA include rhinoconjunctivitis and contact urticaria, but it can also lead to life-threatening reactions, with many patients showing cross-reactivity to various fruits, vegetables, nuts, and cereals.
- Research has identified key allergenic components of Cannabis sativa, but diagnostic testing usually relies on crude allergen extracts, highlighting the need for better understanding and development of personalized diagnosis and management strategies for cannabis-related allergies.
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