Mining of variables from embryo morphokinetics, blastocyst's morphology and patient parameters: an approach to predict the live birth in the assisted reproduction service.

JBRA Assist Reprod

Laboratório de Micromanipulação Embrionária, Department of Biological Sciences, School of Sciences and Languages, Campus Assis, São Paulo State University (UNESP), Assis, SP, Brazil.

Published: October 2020

Based on growing demand for assisted reproduction technology, improved predictive models are required to optimize in vitro fertilization/intracytoplasmatic sperm injection strategies, prioritizing single embryo transfer. There are still several obstacles to overcome for the purpose of improving assisted reproductive success, such as intra- and inter-observer subjectivity in embryonic selection, high occurrence of multiple pregnancies, maternal and neonatal complications. Here, we compare studies that used several variables that impact the success of assisted reproduction, such as blastocyst morphology and morphokinetic aspects of embryo development as well as characteristics of the patients submitted to assisted reproduction, in order to predict embryo quality, implantation or live birth. Thereby, we emphasize the proposal of an artificial intelligence-based platform for a more objective method to predict live birth.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7558892PMC
http://dx.doi.org/10.5935/1518-0557.20200014DOI Listing

Publication Analysis

Top Keywords

assisted reproduction
16
live birth
12
predict live
8
assisted
5
mining variables
4
embryo
4
variables embryo
4
embryo morphokinetics
4
morphokinetics blastocyst's
4
blastocyst's morphology
4

Similar Publications

COVID-19 Impact On Black and Latina Women: Pregnancy and Parenting.

J Racial Ethn Health Disparities

January 2025

Sexual Health and Reproductive Equity Program, School of Social Welfare, University of California, 110 Haviland Hall, MC 7400, Berkeley, CA, 94720-7400, USA.

The coronavirus-19 (COVID-19) pandemic presented unique challenges for pregnant women and birthing individuals, particularly those from Black and Latino communities. Understanding the impact of the pandemic on their experiences is crucial for providing adequate support and care during vulnerable times. This research delves into the specific effects of COVID-19 on maternal stress and resilience.

View Article and Find Full Text PDF

The Future of Parenthood? Examining the Promise and Complexity of Pregnancy Robots in Reproductive Health.

J Med Syst

January 2025

Department of Pharmacology, MGM Medical College & Hospital, MGM Institute of Health Sciences (MGMIHS), Nerul, Navi Mumbai, 400706, India.

Advancements in reproductive technology are now approaching an unprecedented frontier: the pregnancy robot, a potential artificial womb capable of carrying a fetus from fertilization to birth. This innovation, by simulating the natural uterine environment, could redefine pregnancy and parenthood, offering transformative benefits for maternal and infant health. The pregnancy robot promises safer pathways for individuals with medical risks, LGBTQ + couples, and single parents, while also reducing the risks of complications like preeclampsia and preterm birth.

View Article and Find Full Text PDF

Risk of adverse pregnancy outcomes after abnormal hysterosalpingography.

Hum Fertil (Camb)

December 2025

Assisted Reproductive Technologies Unit, Department of Obstetrics and Gynecology, Barzilai University Medical Center, Ashkelon, Israel.

Objective: To investigate the association between an abnormal hysterosalpingogram (HSG) and obstetrical and neonatal outcomes.

Design: A retrospective cohort study comparing outcomes between women with normal versus abnormal tubal patency and uterine cavity on HSG.

Results: Among 2181 women included in the study, 494 (22.

View Article and Find Full Text PDF

Association of Arachidonic Acid Metabolism Related Genes With Endometrial Immune Microenvironment and Oxidative Stress in Coupes With Recurrent Implantation Failure.

Am J Reprod Immunol

January 2025

State Key Laboratory of Reproductive Medicine and Offspring Health, Center for Reproductive Medicine, Institute of Women, Children and Reproductive Health, Shandong University, Jinan, Shandong, China.

Background: Alterations in lipid metabolism were reported to impact human fertility; however, there is limited evidence on the association of lipid metabolism with embryo implantation as well as the etiology of recurrent implantation failure (RIF), especially regarding arachidonic acid metabolism.

Methods: Experimental verification research (16 RIF patients and 30 control patients) based on GEO database analysis (24 RIF patients and 24 control patients). The methods in bioinformatics included differential gene screening, functional enrichment analysis, protein-protein interaction network, cluster analysis, weighted gene co-expression network analysis, and so forth.

View Article and Find Full Text PDF

Multidimensional morphological analysis of live sperm based on multiple-target tracking.

Comput Struct Biotechnol J

December 2024

Department of Assisted Reproduction, Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, Shanghai, China.

Manual semen evaluation methods are subjective and time-consuming. In this study, a deep learning algorithmic framework was designed to enable non-invasive multidimensional morphological analysis of live sperm in motion, improve current clinical sperm morphology testing methods, and significantly contribute to the advancement of assisted reproductive technologies. We improved the FairMOT tracking algorithm by incorporating the distance and angle of the same sperm head movement in adjacent frames, as well as the head target detection frame IOU value, into the cost function of the Hungarian matching algorithm.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!