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One new spirocyclic lactone and one new benzopyran derivative from . | LitMetric

One new spirocyclic lactone and one new benzopyran derivative from .

J Asian Nat Prod Res

Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.

Published: May 2021

One new spirocyclic lactone, terreinlactone C (), and one new benzopyran derivative, 2,2-dimethyl-3-hydroxychroman-6-aldehyde (), were discovered from the fungus . The chemical structures of compounds and were elucidated by detailedly analyzing NMR and HRESIMS data. Compound is the first natural product with a 1-oxaspiro[4.5]decan-2-one ring system and a possible biogenetic pathway is proposed. Two compounds were tested for their cytotoxic activities against five human cancer cell lines.[Formula: see text].

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Source
http://dx.doi.org/10.1080/10286020.2020.1747052DOI Listing

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