Erasure machine: Inverse Ising inference from reweighting of observation frequencies.

Phys Rev E

Laboratory of Biological Modeling, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA.

Published: March 2020

Maximum likelihood estimation (MLE) is fundamental to system inference for stochastic systems. In some generality, MLE will converge to the correct model in the infinite data limit. In the context of physical approaches to system inference, such as Boltzmann machines, MLE requires the arduous computation of partition functions summing over all configurations, both observed and unobserved. We present a conceptually transparent data-driven inference computation based on a reweighting of observed configuration frequencies that allows us to recast the inference problem as a simpler calculation. Modeling our approach on the high-temperature limit of statistical physics, we reweight the frequencies of observed configurations by multiplying with reciprocals of Boltzmann weights and update the Boltzmann weights iteratively to make these products close to the high-temperature limit of the Boltzmann weights. This converts the required partition function computation in the reweighted MLE to a tractable leading-order high-temperature term. We show that this is a convex optimization at each step. Then, for systems with a large number of degrees of freedom where other approaches are intractable, we demonstrate that this data-driven algorithm gives accurate inference with both synthetic data and two real-world examples.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8491144PMC
http://dx.doi.org/10.1103/PhysRevE.101.032107DOI Listing

Publication Analysis

Top Keywords

boltzmann weights
12
system inference
8
high-temperature limit
8
inference
6
erasure machine
4
machine inverse
4
inverse ising
4
ising inference
4
inference reweighting
4
reweighting observation
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!