A method for preparation of carboxy-protected amino acid conjugates of glycyrrhizinic acid with the use of -hydroxybenzotriazole, 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide, and methyl esters of L-amino acids (phenylalanine, tyrosine, leucine, isoleucine, and methionine) in 85-90% yield was developed. The structure of the prepared compounds was confirmed by IR and C NMR spectra.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7104129 | PMC |
| http://dx.doi.org/10.1134/S1070363216040113 | DOI Listing |
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