At a concentration of 2 μg/ml, neither amphotericin B nor deoxycholate had an inactivating effect upon transmissible gastroenteritis Coronavirus in-fectivity. However, amphothericin B stimulated plaque formatin in agarose and facilitated the entry of viral RNA into swine testis cells. The combination of amphotericin B + deoxycholate inactivated virus infectivity and induced a decrease in plaque diameter. Finally, in the presence of these agents, the production of infectious virus and interferon was unchanged.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7135538 | PMC |
| http://dx.doi.org/10.1016/S0769-2617(87)80019-9 | DOI Listing |
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