In this paper, we study epidemic spreading in metapopulation networks wherein each node represents a subpopulation symbolizing a city or an urban area and links connecting nodes correspond to the human traveling routes among cities. Differently from previous studies, we introduce a heterogeneous infection rate to characterize the effect of nodes' local properties, such as population density, individual health habits, and social conditions, on epidemic infectivity. By means of a mean-field approach and Monte Carlo simulations, we explore how the heterogeneity of the infection rate affects the epidemic dynamics, and find that large fluctuations of the infection rate have a profound impact on the epidemic threshold as well as the temporal behavior of the prevalence above the epidemic threshold. This work can refine our understanding of epidemic spreading in metapopulation networks with the effect of nodes' local properties.
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http://dx.doi.org/10.1016/j.physa.2014.08.056 | DOI Listing |
Int J Mol Sci
December 2024
Abel Salazar Institute of Biomedical Sciences (ICBAS), University of Porto, 4050-313 Porto, Portugal.
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is a respiratory virus that emerged in late 2019 and rapidly spread worldwide, causing the COVID-19 pandemic. The spike glycoprotein (S protein) plays a crucial role in viral target recognition and entry by interacting with angiotensin, converting enzyme 2 (ACE2), the functional receptor for the virus, via its receptor binding domain (RBD). The RBD availability for this interaction can be influenced by external factors, such as fatty acids.
View Article and Find Full Text PDFAnimals (Basel)
January 2025
Experimental Zooprophylactic Institute of Lombardy and Emilia Romagna (IZSLER), "Bruno Ubertini", Diagnostic Section of Piacenza, Italy Via Strada Della Faggiola 1, 29027 Podenzano, PC, Italy.
is diffused worldwide, and subsp. is spread worldwide with many serovars associated with the infection of domestic bovines. The most spread are .
View Article and Find Full Text PDFMalar J
January 2025
Global Health and Tropical Medicine, GHTM, Associate Laboratory in Translation and Innovation Towards Global Health, LA-REAL, Instituto de Higiene e Medicina Tropical, IHMT, Universidade NOVA de Lisboa, UNL, Rua da Junqueira 100, 1349-008, Lisbon, Portugal.
Background: Malaria is the parasitic disease with the highest global morbidity and mortality. According to estimates from the World Health Organization (WHO), there were around 249 million cases in 2022, with 3.4% occurring in Angola.
View Article and Find Full Text PDFBMC Public Health
January 2025
Zambia Field Epidemiology Training Program, Lusaka, Zambia.
Background: Geographical factors can affect infectious disease transmission, including SARS-CoV-2, a virus that is spread through respiratory secretions. Prioritization of surveillance and response activities during a pandemic can be informed by a pathogen's geographical transmission patterns. We assessed the relationship between geographical factors and SARS-CoV-2 prevalence in Zambia.
View Article and Find Full Text PDFBMC Public Health
January 2025
Department of Medical Nursing, School of Nursing, College of Medicine and Health Sciences, University of Gondar, P.O. BOX 196, Gondar City, Ethiopia.
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