AI Article Synopsis

  • Dermatological services in Laos are limited, leaving a gap in data about common allergens affecting local populations, especially children with atopic dermatitis.
  • The study focused on patch testing 50 pediatric patients in Vientiane using TRUE Test® panels, identifying allergens and recording reactions.
  • Results showed that 30% of the children tested positive for common allergens, with gold, nickel, and formaldehyde being the most prevalent, providing valuable insights for clinicians to guide families on allergen avoidance.

Article Abstract

Background: Dermatological services in Laos, South East Asia are limited mainly to the capital and patch testing is currently not available, so no data exists regarding the common cutaneous allergens in this population.

Objectives: The aim of this study was to document common allergens in paediatric patients with atopic dermatitis attending the allergy clinic in the capital, Vientiane.

Patients/materials/methods: Fifty paediatric patients with atopic dermatitis were patch tested using TRUE Test® panels 1 to 3 (35 allergens). Readings were taken at Days 2 and 4.

Results: Twenty-six positive patch tests were recorded on Day 4 in 15 children (30%). The most common allergens were: gold (18%), nickel (10%), formaldehyde (6%) and p-Phenylenediamine (6%). Other positive allergens were potassium dichromate (2%), cobalt dichloride (2%), Bronopol (2%), paraben mix (2%), fragrance mix 1 (2%) and neomycin (2%). The majority of the patients with positive reactions were female.

Conclusions: This study represents the first documented patch test results in the Lao population. It is hoped that these findings will help clinicians to advise the families of children with atopic dermatitis on common allergens to avoid and inform future work on contact dermatitis in this population.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7156065PMC
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0231455PLOS

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