Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9364893 | PMC |
| http://dx.doi.org/10.2967/jnumed.119.240457 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
3D Printable Poly(-isopropylacrylamide) Microgel Suspensions with Temperature-Dependent Rheological Responses.
ACS Appl Polym Mater
December 2024
Department of NanoEngineering, University of California San Diego, La Jolla, California 92093, United States.
Microgel suspensions have garnered significant interest in fundamental research due to their phase transition between liquid-like to paste-like behaviors stemming from tunable interparticle and particle-solvent interactions. Particularly, stimuli-responsive microgels undergo faster volume changes in response to external stimuli in comparison to their bulk counterparts, while maintaining their structural integrity. Here, concentrated and diluted suspensions of poly(-isopropylacrylamide) (PNIPAm) microgels are dispersed to different packing fractions in water for the characterizations of temperature-responsive rheological responses.
View Article and Find Full Text PDFA 3D-Printable Cell Array for In Vitro Breast Cancer Modeling.
Int J Mol Sci
December 2024
Department of Experimental Medicine, University of Rome "Tor Vergata", Via Montpellier 1, 00133 Rome, Italy.
Breast cancer is the most common cancer and the second leading cause of cancer-related death in women. In advanced stages of the disease, breast cancer can spread and metastasize to the bone, contributing to malignant progression. The roles of tissue stiffness and remodeling of the tumor microenvironment are relevant in influencing cancer progression and invasiveness, but they are still poorly understood.
View Article and Find Full Text PDFAdditively Manufactured 3D Clamp-Culture System for the Investigation of Material-Cell Interactions in Multi-Material Hybrid Scaffolds for Musculoskeletal Tissue Defects.
J Biomed Mater Res B Appl Biomater
November 2024
Charité - Universitätsmedizin Berlin, Berlin, Germany.
The emergence of hybrid scaffolds, blending biomaterials with diverse properties, offers promise in musculoskeletal tissue engineering. However, a need for in vitro platforms investigating biological behavior and the interplay of different load-bearing and colonizable synthetic bone substitute materials remains. Herein, we present a novel, in-house producible, and scalable clamp culture system designed for facile in vitro analysis of interactions between biomaterials, hydrogels, and cells.
View Article and Find Full Text PDFConsiderations of growth factor and material use in bone tissue engineering using biodegradable scaffolds in vitro and in vivo.
Sci Rep
October 2024
Bone and Joint Research Group, Centre for Human Development, Stem Cells and Regeneration, Institute of Developmental Sciences, University of Southampton, Southampton, SO16 6YD, United Kingdom.
Bone tissue engineering aims to harness materials to develop functional bone tissue to heal 'critical-sized' bone defects. This study examined a robust, coated poly(caprolactone) trimethacrylate (PCL-TMA) 3D-printable scaffold designed to augment bone formation. Following optimisation of the coatings, three bioactive coatings were examined, i) elastin-like polypeptide (ELP), ii) poly(ethyl acrylate) (PEA), fibronectin (FN) and bone morphogenetic protein-2 (BMP-2) applied sequentially (PEA/FN/BMP-2) and iii) both ELP and PEA/FN/BMP-2 coatings applied concurrently.
View Article and Find Full Text PDFPersistent Photoluminescence and Mechanoluminescence of a Highly Sensitive Pressure and Temperature Gauge in Combination with a 3D-Printable Optical Coding Platform.
Adv Sci (Weinh)
November 2024
Faculty of Chemistry, Adam Mickiewicz University, Uniwersytetu Poznańskiego 8, Poznań, 61-614, Poland.
Distinct types of luminescence that are activated by various stimuli in a single material offer exciting developmental opportunities for functional materials. A versatile sensing platform that exhibits photoluminescence (PL), persistent luminescence (PersL), and mechanoluminescence (ML) is introduced, which enables the sensitive detection of temperature, pressure, and force/stress. The developed SrMgSiO:Eu/Dy material exhibits a linear relationship between ML intensity and force and can be used as an ML stress sensor.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!