AI Article Synopsis
- Benign convulsions with gastroenteritis involve a series of seizures that can occur during illness.
- A study administered lacosamide, a new sodium channel blocker, to five patients aged 17 to 33 months who had 1-4 generalized convulsions lasting from 30 to 120 seconds.
- After receiving a single dose of lacosamide (2 mg/kg), the seizures stopped without any reported side effects.
Article Abstract
Benign convulsions with gastroenteritis are characterized by a cluster of seizures. Sodium channel blockers are efficacious. We prescribed lacosamide, a new channel blocker, for five patients. Patient age ranged from 17 to 33 months; all five experienced 1-4 generalized convulsions persisting for 30-120 s. One patient exhibited a transient splenial lesion on head magnetic resonance imaging. All received one dose (2 mg/kg) of lacosamide. The convulsions ceased, and no adverse drug effect was noted. A single dose of lacosamide was effective and well-tolerated in five patients with benign convulsions with gastroenteritis.
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| http://dx.doi.org/10.1016/j.braindev.2020.03.006 | DOI Listing |
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