Background: Modeling the spatio-temporal characteristics of substantiated child maltreatment risk has significant implications for child welfare policy.
Objective: This study quantifies the spatiotemporal risk of child abuse and neglect in New Mexico at the census tract level over 9 years, identifies areas of increased risk, and evaluates the role of multiple measures of social and housing insecurity on substantiated child maltreatment referrals.
Participants And Setting: Child maltreatment substantiation data across 499 census tracts from 2007 to 2015 were obtained from the New Mexico Department of Public Health.
Methods: Substantiated referral counts were analyzed within census tracts with Bayesian hierarchical space-time models using Laplace approximation. Standardized incidence ratios, spatial risk, and probability exceedances were calculated and mapped.
Results: Multiple neighborhood structural factors were associated with an increased risk of substantiated child maltreatment, including the eviction rate (Incidence Density Ratio [IDR] = 1.09 [95 % CrI = 1.01-1.12]), rent burden (IDR = 1.11 [95 % CrI = 1.01-1.13]), urban tracts (IDR = 1.36 [95 % CrI = 1.05-1.77]), food desert tracts (IDR = 1.21 [95 % CrI = 1.04-1.41]), low income tracts (IDR = 1.27 [95 % CrI = 1.09-1.49]), percent of households with no vehicle access ([IDR] = 1.27 [95 % CrI = .247-6.47]), and percent of persons with a disability (IDR = 1.05 [95 % CrI = 1.03-1.06]). The racial/ethnic diversity ratio, however, was associated with lower incidence of child maltreatment allegation risk (IDR = .988 [95 % CrI = .982-.995]).
Conclusions: Population-based child abuse and neglect prevention and intervention efforts should be aided by the characteristics of neighborhoods that demonstrate strong spatial patterns of household and housing vulnerability, particularly in low income, racially segregated neighborhoods.
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http://dx.doi.org/10.1016/j.chiabu.2020.104472 | DOI Listing |
Clin Infect Dis
January 2025
EPIUnit - Instituto de Saúde Pública, Universidade do Porto, Porto, Portugal.
Background: Higher than standard doses of rifampicin could improve the treatment outcome of drug-susceptible tuberculosis without compromising the safety of patients.
Methods: We performed a systematic review of prospective clinical studies including adults with pulmonary and extrapulmonary TB receiving rifampicin doses above 10mg/kg/day. We extracted the data on overall adverse events (AE), hepatic AE, sputum culture conversion (SCC) at week 8, recurrence, mortality, and pharmacokinetics.
Int J Infect Dis
January 2025
School of Population Health, Faculty of Health Sciences, Curtin University, Australia; Geospatial and Tuberculosis Research Team, Telethon Kids Institute, Australia. Electronic address:
Objective: To map subnational and local prevalence of drug-resistant tuberculosis (DR-TB) across Africa.
Methods: We assembled a geolocated dataset from 173 sources across 31 African countries, comprising drug susceptibility test results and covariate data from publicly available databases. We used Bayesian model-based geostatistical framework with multivariate Bayesian logistic regression model to estimate DR-TB prevalence at lower administrative levels.
Alzheimers Dement
December 2024
Swansea University, Swansea, United Kingdom
Background: The emergence of new biomarkers for Alzheimer’s disease is accompanied by the urgent need to evaluate their diagnostic performance in comparison to existing technologies. Meta‐analysis methods make best use of the available evidence by synthesizing all relevant published studies. Meta‐analytic models that estimate comparative diagnostic accuracy are key to informing healthcare decision‐making around which tests should be used in clinical practice.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Baylor College of Medicine, Houston, TX, USA
Background: Apathy is marked by diminished motivation and goal‐directed behavior, prevalent in neurodegenerative diseases like Alzheimer’s disease (AD) and Parkinson’s disease (PD). Effort‐based decision‐making paradigms (EBDM), which require choices between tasks of varying effort levels for varying rewards, are effective assessments of goal‐directed behavior. Using a transdiagnostic approach, we are examining the neurodegeneration of networks on apathy and EBDM.
View Article and Find Full Text PDFFront Pediatr
December 2024
Department of Pediatrics, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China.
Background: Premature births has imposed substantial burdens on medical resources. Consequently, a specialized team was established and a model focused on early intervention, namely the Delivery Room Intensive Care Unit (DICU) emphasizing "care, support, and treatment" was introduced and its impact on the morbidity and mortality outcomes of newborns was assessed. Additionally, we aimed to develop a nomogram model for predicting the risk of intraventricular hemorrhage (IVH) in preterm infants.
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