HLA-B*27:199 differs from HLA-B*27:05:02:01 by one nucleotide substitution (c.814G>T) with one amino acid change (p.V248L).
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http://dx.doi.org/10.1111/tan.13895 | DOI Listing |
Cureus
December 2024
Department of Ophthalmology, King Abdulaziz Medical City, Ministry of National Guard Health Affairs, Jeddah, SAU.
Optic nerve disorders significantly contribute to visual impairment with irreversible visual deficits. Current treatments have limited efficacy in resolving chronic visual deficits, necessitating novel therapeutic strategies. Neurorehabilitation techniques, including repetitive transorbital alternating current stimulation (rtACS), have emerged as promising approaches to restore lost visual function through the ability to modulate brain activity.
View Article and Find Full Text PDFFront Plant Sci
January 2025
Beijing Key Lab of Digital Plant, Information Technology Research Center, Beijing Academy of Agriculture and Forestry Sciences, Beijing, China.
The stomatal phenotype is a crucial microscopic characteristic of the leaf surface, and modulating the stomata of maize leaves can enhance photosynthetic carbon assimilation and water use efficiency, thereby playing a vital role in maize yield formation. The evolving imaging and image processing technologies offer effective tools for precise analysis of stomatal phenotypes. This study employed Jingnongke 728 and its parental inbred to capture stomatal images from various leaf positions and abaxial surfaces during key reproductive stages using rapid scanning electron microscopy.
View Article and Find Full Text PDFFront Plant Sci
January 2025
Institute of Crop Science, Huzhou Academy of Agriculture Sciences, Huzhou, China.
With the rapid advancement of plant phenotyping research, understanding plant genetic information and growth trends has become crucial. Measuring seedling length is a key criterion for assessing seed viability, but traditional ruler-based methods are time-consuming and labor-intensive. To address these limitations, we propose an efficient deep learning approach to enhance plant seedling phenotyping analysis.
View Article and Find Full Text PDFJACC Adv
February 2025
Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.
Background: Clonal hematopoiesis of indeterminate potential (CHIP) has been linked to intensified systemic inflammation and represents a novel risk factor for atherosclerotic cardiovascular diseases, including aortic stenosis (AS).
Objectives: This study aimed to assess the clinical impact of CHIP in a cohort of severe AS patients undergoing transcatheter aortic valve implantation (TAVI).
Methods: We enrolled 110 severe AS patients in this retrospective study.
BMJ Oncol
January 2024
Novelna Inc, Palo Alto, California, USA.
Objective: Early detection of cancer is crucial for reducing the global burden of cancer, but effective screening tests for many cancers do not exist. This study aimed to develop a novel proteome-based multi-cancer screening test that can detect early-stage cancers with high accuracy.
Methods And Analysis: We collected plasma samples from 440 individuals, healthy and diagnosed with 18 early-stage solid tumours.
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