Purpose: The aim of this study was to evaluate condylar asymmetry in different skeletal patterns with cone-beam CT (CBCT).
Methods: A total of 110 subjects aged from 18 to 30 years were selected from patients who had undergone CBCT examinations retrospectively. All the subjects were divided into three groups according to their skeletal patterns: Class Ⅰ (Cl Ⅰ: 0°≤ANB≤5°), Class Ⅱ (Cl Ⅱ: ANB>5°) and Class Ⅲ (Cl Ⅲ: ANB<0°). In addition, each group was further divided into two subgroups according to genders. Condylar (Co-Sig), ramus (Go-Sig) and condyle-plus-ramus (Co-Go) asymmetry were assessed by identifying landmarks on the reconstructed images with a 3-dimentional (3D) reference plane. The coordinates of the landmarks were calculated statistically. The data were analyzed statistically with SPSS17.0 software package.
Results: The condyle-plus-ramus and ramus asymmetry (Co-Go R-L and Go-Sig R-L) were affected by the ANB angle (P<0.05) respectively, and the differences mainly came from the y coordinate (P<0.05). When comparing the two sides of the three groups respectively, the Co-Go, Go-Sig and Co-Sig of some patients had gender difference and left-right difference. The z coordinate of point Menton (Me) had significant difference (P<0.05) caused by different skeletal patterns, while the coordinates of x and y were similar (P>0.05).
Conclusions: Condyle-plus-ramus and the ramus asymmetry were affected by different skeletal patterns and the differences were caused by the height primarily. Patients of Class Ⅲ usually manifest mandibular protrusion while Class Ⅱ with mandibular retrognathism. Whether the degree of chin deviation differs according to the condylar asymmetry needs further investigation.
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Nat Commun
December 2024
Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong, China.
Probing regional glycogen metabolism in humans non-invasively has been challenging due to a lack of sensitive approaches. Here we studied human muscle glycogen dynamics post-exercise with a spatial resolution of millimeters and temporal resolution of minutes, using relayed nuclear Overhauser effect (glycoNOE) MRI. Data at 5T showed a homogeneous distribution of glycogen in resting muscle, with an average concentration of 99 ± 13 mM.
View Article and Find Full Text PDFNat Commun
December 2024
Longitudinal Studies Section, Translational Gerontology Branch, National Institute on Aging, Baltimore, MD, USA.
Impaired muscle mitochondrial oxidative capacity is associated with future cognitive impairment, and higher levels of PET and blood biomarkers of Alzheimer's disease and neurodegeneration. Here, we examine its associations with up to over a decade-long changes in brain atrophy and microstructure. Higher in vivo skeletal muscle oxidative capacity via MR spectroscopy (post-exercise recovery rate, k) is associated with less ventricular enlargement and brain aging progression, and less atrophy in specific regions, notably primary sensorimotor cortex, temporal white and gray matter, thalamus, occipital areas, cingulate cortex, and cerebellum white matter.
View Article and Find Full Text PDFJ Orthop Surg Res
December 2024
School of Acupuncture, Moxibustion and Tuina, Beijing University of Chinese Medicine, Beijing, 100029, People's Republic of China.
Background: Tuina is an effective treatment for the decrease of skeletal muscle atrophy after peripheral nerve injury. However, the underlying mechanism of action remains unclear. This study aimed to explore the underlying mechanisms of tuina in rats with sciatic nerve injury (SNI).
View Article and Find Full Text PDFSkelet Muscle
December 2024
Rehabilitation Sciences Institute, University of Toronto, Toronto, ON, Canada.
Background: INTER- and INTRAmuscular fat (IMF) is elevated in high metabolic states and can promote inflammation. While magnetic resonance imaging (MRI) excels in depicting IMF, the lack of reproducible tools prevents the ability to measure change and track intervention success.
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Am J Orthod Dentofacial Orthop
December 2024
Department of Orthodontics, Teerthanker Mahavir Dental College and Research Centre, Teerthanker Mahaveer University, Moradabad, Uttar Pradesh, India.
Introduction: The primary objective of this study was to assess the 3-dimensional position of the mandibular canal (MC) in different craniofacial patterns to know about the safe placement of temporary skeletal anchorage devices using cone-beam computed tomography (CBCT). The secondary objectives were to assess sex differences and correlate the MC position with various factors.
Methods: This prospective, observational study was conducted on 90 patients, divided into 3 groups based on the sagittal pattern: skeletal Class I, Class II, and Class III.
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