The role of magnesium in biomaterials related infections.

Colloids Surf B Biointerfaces

University of Extremadura, Department of Applied Physics, Badajoz, Spain; Networking Research Center on Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Badajoz, Spain; University Institute of Extremadura Sanity Research (iNube), Badajoz, Spain.

Published: July 2020

Magnesium is currently increasing interest in the field of biomaterials. An extensive bibliography on this material in the last two decades arises from its potential for the development of biodegradable implants. In addition, many researches, motivated by this progress, have analyzed the performance of magnesium in both in vitro and in vivo assays with gram-positive and gram-negative bacteria in a very broad range of conditions. This review explores the extensive literature in recent years on magnesium in biomaterials-related infections, and discusses the mechanisms of the Mg action on bacteria, as well as the competition of Mg and/or synergy with other divalent cations in this subject.

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http://dx.doi.org/10.1016/j.colsurfb.2020.110996DOI Listing

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