A Vibriophage Takes Antirepression to the Next Level.

Cell Host Microbe

Laboratory of Molecular Microbiology, Global Health Institute, School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne (EPFL), CH-1015 Lausanne, Switzerland. Electronic address:

Published: April 2020

Since its isolation by Esther Lederberg, phage lambda and its repressor protein CI have contributed substantially to the advancement of molecular biology. In this issue of Cell Host & Microbe, Silpe et al. (2020) characterize the antirepressor Qtip of Vibrio phage VP882, which through CI sequestration triggers a lytic switch.

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Source
http://dx.doi.org/10.1016/j.chom.2020.03.019DOI Listing

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