Hexatic phase in a model of active biological tissues.

Soft Matter

School of Physical and Mathematical Science, Nanyang Technological University, Singapore. and CNR-SPIN, Dipartimento di Scienze Fisiche, Università di Napoli Federico II, I-80126, Napoli, Italy.

Published: April 2020

In many biological processes, such as wound healing, cell tissues undergo an epithelial-to-mesenchymal transition, which is a transition from a more rigid to a more fluid state. Here, we investigate the solid/fluid transition of cell tissues within the framework of the self-propelled Voronoi model, which accounts for the deformability of the cells, for their many-body interactions, and for their polarized motility. The transition is controlled by two parameters, respectively accounting for the strength of the self-propelling force of the cells, and for the mechanical rigidity of the cells. We find the melting transition to occur via a continuous solid-hexatic transition followed by a continuous hexatic-liquid transition, as in the Kosterlitz, Thouless, Halperin, Nelson, and Young scenario. This finding indicates that the hexatic phase may have an unexpected biological relevance.

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http://dx.doi.org/10.1039/d0sm00109kDOI Listing

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