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| http://dx.doi.org/10.1016/j.tmaid.2020.101656 | DOI Listing |
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Impact of the COVID-19 pandemic on dengue in Brazil: Interrupted time series analysis of changes in surveillance and transmission.
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Institute of Mathematics and Computer Science, University of São Paulo, São Carlos, SP, Brazil.
Measures to curb the spread of SARS-CoV-2 impacted not only COVID-19 dynamics, but also other infectious diseases, such as dengue in Brazil. The COVID-19 pandemic disrupted not only transmission dynamics due to changes in mobility patterns, but also several aspects of surveillance, such as care seeking behavior and clinical capacity. However, we lack a clear understanding of the overall impact on dengue in different parts of Brazil and the contribution of individual causal drivers.
View Article and Find Full Text PDFRapid human movement and dengue transmission in Bangladesh: a spatial and temporal analysis based on different policy measures of COVID-19 pandemic and Eid festival.
Infect Dis Poverty
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Ecosystem Change and Population Health Research Group, Centre for Immunology and Infection Control, School of Public Health and Social Work, Queensland University of Technology, Kelvin Grove, Brisbane, QLD, 4059, Australia.
Background: Rapid human movement plays a crucial role in the spatial dissemination of the dengue virus. Nevertheless, robust quantification of this relationship using both spatial and temporal models remains necessary. This study aims to explore the spatial and temporal patterns of dengue transmission under various human movement contexts.
View Article and Find Full Text PDFBackground: The rapid increase in nucleotide sequence data generated by next-generation sequencing (NGS) technologies demands efficient computational tools for sequence comparison. Alignment-based methods, such as BLAST, are increasingly overwhelmed by the scale of contemporary datasets due to their high computational demands for classification. This study evaluates alignment-free (AF) methods as scalable and rapid alternatives for viral sequence classification, focusing on identifying techniques that maintain high accuracy and efficiency when applied to extremely large datasets.
View Article and Find Full Text PDFReemerging Infectious Diseases and Neuroimmunologic Complications.
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January 2025
Department of Neurology, University of Pennsylvania, Philadelphia.
During the past decade (and beyond), neurologists have become aware of the emergence, persistence, and consequences of some familiar and new infections affecting the nervous system. Even among the familiar CNS infections, such as herpes virus, polyoma virus/JC, influenza, arbovirus, and hepatitis, challenges remain in developing effective antiviral treatments and treatments of postinfection sequelae. With the changing environment and increased global travel, arthropod vectors that mediate zoonotic disease transmission have spread unfamiliar viruses such as West Nile virus, dengue, chikungunya, equine encephalitis, and Zika, among others.
View Article and Find Full Text PDFA Systematic Review on the Antimicrobial Activity of Andrographolide.
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Department of Medical Microbiology and Parasitology, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, Kelantan 16150, Malaysia.
Andrographolide, a bioactive compound from Andrographis paniculata, has gained attention for its antimicrobial properties, which include antibacterial, antiviral, antifungal, and antiprotozoal effects. As an herbal extract used in traditional medicines, andrographolide also shows promise for developing new antimicrobial agents, especially in the fight against rising antimicrobial resistance. Following the PRISMA 2020 guidelines, 16 peer-reviewed studies published from 2010 to 2024 and focusing on andrographolide's effects on bacteria, viruses, fungi, and protozoa were reviewed.
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