Acquired aplastic anemia is a T-cell–mediated autoimmune bone marrow aplasia, without a known etiologic trigger. Clonal expansion of CD8 effector T lymphocytes can occur following vaccination and accompany graft dysfunction or aplastic anemia relapse.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7160279PMC
http://dx.doi.org/10.1182/bloodadvances.2019000853DOI Listing

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