AI Article Synopsis

  • - The study aimed to evaluate how increased experience of a surgical team in fetal myelomeningocele (fMMC) repair impacts maternal and fetal/neonatal outcomes over different time periods.
  • - Researchers compared outcomes from two cohorts: an early period (2005-2011) and a current period (2012-2015), alongside a randomized study involving 78 patients, finding low maternal morbidity and a significant drop in preterm labor rates.
  • - The increased experience of the surgical team led to improved outcomes, notably a decrease in iatrogenic preterm labor from 34.1% to 23.9%, while the rate of hindbrain herniation reduction remained similar across the cohorts.

Article Abstract

Objectives: We aimed to show how increased experience of a surgery team in fMMC repair influences maternal and fetal/neonatal outcomes.

Material And Methods: We compare perinatal results of fMMC repair in our Fetal Surgery Center (FSC) in cohort groups for the early period (2005-2011 year; previous - PFSC, n = 46) and current period (2012-2015 year; current - CFSC, n = 74) to results of the randomized Management of Myelomeningocele Study (MOMS, 78 patients).

Results: The maternal morbidity due to fMMC repair was low and there was no difference comparing CFSC to PFSC and MOMS. The frequency of iatrogenic preterm labor (iPTL) ≤ 30 weeks of gestation decreased from 34.1% in PFSC to 23.9% in CFSC. Iatrogenic preterm premature rupture of membranes (iPPROM) was a common complication after fMMC repair in all cohorts. The total reduction rate of hindbrain hernation (HH) was similar in CFSC - 90.3% and PFSC - 82.1%.

Conclusions: The increasing experience of our surgery team in fMMC repair majorly decreased the risk of iPTL.

Download full-text PDF

Source
http://dx.doi.org/10.5603/GP.2020.0028DOI Listing

Publication Analysis

Top Keywords

fmmc repair
20
fetal surgery
8
experience surgery
8
surgery team
8
team fmmc
8
iatrogenic preterm
8
fmmc
5
repair
5
open fetal
4
surgery
4

Similar Publications

Article Synopsis
  • No established protocols for fetal cardiac monitoring exist for fetoscopic myelomeningocele (fMMC) repair; the study aimed to assess the feasibility of continuous fetal echocardiography during this procedure and correlate Doppler changes with fetal cardiac function.
  • Continuous fetal echocardiography was conducted in real-time for patients undergoing fMMC repair, monitoring various cardiac indicators including fetal heart rate and blood flow in different vessels.
  • While abnormalities were found in several patients, especially in umbilical artery flow, most cardiac functions remained normal, indicating that continuous monitoring can be effectively implemented during fMMC surgeries with minor temporary changes.
View Article and Find Full Text PDF

Objective: The aim of this study was to evaluate the incidence of spinal inclusion cyst (sIC) formation after open fetal myelomeningocele (fMMC) repair and the effect of dural patch closure.

Methods: The authors conducted a retrospective review of patients who underwent open fMMC repair at their institution between March 2011 and June 2020. All patients met the criteria for intervention defined by the Management of Myelomeningocele Study (MOMS).

View Article and Find Full Text PDF

In our response to, "Parental request for non-resuscitation in fetal myelomeningocele repair: an analysis of the novel ethical tensions in fetal intervention" by Wolfe and co-authors, we argue that parental authority should guide resuscitation decision-making for a fetus at risk for preterm delivery as a complication of fetal myelomeningocele (fMMC) repair. Due to the elevated morbidity and mortality risks of combined myelomeningocele, extreme prematurity, and fetal hypoxia, parents' values regarding the acceptability of possible outcomes should be elicited and their preferences honored. Ethical decision-making in these situations must also consider the broader context of the fetal-maternal dyad.

View Article and Find Full Text PDF

Introduction: The main aim of the fetal surgery of myelomeningocele (MMC) is the improvement in prognosis for children with this defect and at the same time high safety of the procedure for mother and fetus.

Objective: The aim of the study was to determine the effectiveness of alternative hysterotomy technique for fetal surgery of MMC in prevention of essential perinatal complications.

Methods: Forty-nine pregnant women diagnosed with fetal MMC (fMMC) who underwent classic hysterotomy without the use of stapler formed the study cohort.

View Article and Find Full Text PDF

Objective: To systematically categorise all maternal and fetal intervention-related complications after open fetal myelomeningocele (fMMC) repair of the first 124 cases operated at the Zurich Centre for Fetal Diagnosis and Therapy.

Design: A prospective cohort study.

Setting: Single centre.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!