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http://dx.doi.org/10.1097/EJA.0000000000001163 | DOI Listing |
Ann Surg Oncol
August 2024
Margaret West Comprehensive Breast Center, West Cancer Center, Germantown, TN, USA.
Eur J Cancer
May 2024
Division of Cancer Prevention and Genetics, IEO, European Institute of Oncology IRCCS, Milan, Italy.
Background And Aim: Ductal carcinoma in situ (DCIS) is a non-obligate precursor of invasive breast cancer with highly variable clinical behavior, but risk stratification is still challenging. We sought to identify immune-related gene expression signatures of pure DCIS associated with different risks of breast cancer recurrence.
Methods: A retrospective nested case-control study of 143 pure DCIS was performed including 70 women with subsequent ipsilateral breast event (IBE, in situ or invasive; cases) and 73 DCIS women with no IBE and matched for age, tumor size, treatment, hormone receptors/HER2 status, and follow-up time (controls).
Clin Nucl Med
September 2023
Department of Nuclear Medicine and Molecular Imaging, Singapore General Hospital, Singapore
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