AI Article Synopsis
- The Mirena IUD is a hormone-releasing contraceptive, with rare cases of pregnancy and unknown fetal effects.
- Four female patients experienced genital virilization after pregnancy while having a retained Mirena IUD.
- All patients had normal chromosomal and hormonal evaluations, and three successfully underwent flap vaginoplasty, leading to good cosmetic results.
Article Abstract
The Mirena intrauterine device (IUD) is a hormone-secreting contraceptive device. Pregnancy with the Mirena is rare and effects to the fetus are unknown. Here we present four females with genital virilization after pregnancy with persistent Mirena IUD. All patients had a 46, XX karyotype and normal hormone evaluation. All underwent exam under anesthesia, demonstrating posterior labial fusion and short urogenital sinus with normal bladder, urethra, vagina, and cervix. Three of four patients underwent flap vaginoplasty without complications and good cosmetic outcomes. This series suggests that persistent levonorgestrel-secreting IUD during pregnancy is associated with genital virilization in female fetuses.
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| http://dx.doi.org/10.1016/j.jpurol.2020.03.008 | DOI Listing |
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