Flexible and wearable piezoelectric bio e-skin (PBio-e-skin) based on electrospun poly(l-lactic acid) PLLA nanofiber membrane is demonstrated for non-invasive human physiological signal monitoring and detecting dynamic tactile stimuli. The molecular orientations of the C[double bond, length as m-dash]O dipoles by electrospinning technique result in a longitudinal piezoelectric charge co-efficient (d) value of ∼(3 ± 1) pm V realized by piezoresponse force microscopy, allowing the PBio-e-skin for pressure sensing applications. The robust mechanical strength (Young's modulus ∼50 MPa) of nanofiber membrane ensures PBio-e-skin's superior operational stability over 375 000 cycles. Owing to the superior mechanosensitivity of ∼22 V N, PBio-e-skin has the ability to measure subtle movement of muscle in the internal organs such as esophagus, trachea, motion of joints and arterial pressure by recognition of strains on human skin. This flexible and light weight PBio-e-skin precisely detects vital signs and provides important clinical insights without using any external power source. Eventually, the low cost, environmental friendly PBio-e-skin will have a huge impact in a broad range of applications including self-powered wearable health care systems, human-machine interfacing devices, artificial intelligence and prosthetic skin.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1039/c7tb01439b | DOI Listing |
J Biomed Opt
June 2024
Food and Drug Administration, Center for Devices and Radiological Health, Silver Spring, Maryland, United States.
Significance: Pulse oximeter measurements are commonly relied upon for managing patient care and thus often require human testing before they can be legally marketed. Recent clinical studies have also identified disparities in their measurement of blood oxygen saturation by race or skin pigmentation.
Aim: The development of a reliable bench-top performance test method based on tissue-simulating phantoms has the potential to facilitate pre-market assessment and the development of more accurate and equitable devices.
Cureus
December 2024
Immunohemotherapy Department, Unidade de Saúde Local da Região de Aveiro, Aveiro, PRT.
Intravenous iron is commonly used to treat anemia related to chronic illnesses, but venous extravasation, an uncommon side effect of intravenous iron, can result in persistent skin discoloration. This report presents the case of a female patient who experienced venous extravasation following intravenous iron administration, with data collected from her patient record. Although venous extravasation is a rare adverse effect, it is important for both patients and healthcare providers to recognize this potential complication.
View Article and Find Full Text PDFCureus
December 2024
Internal Medicine, Baylor Scott and White Health, Fort Worth, USA.
Unlike other skin and soft tissue infections, necrotizing fasciitis (NF) is a rare and potentially life-threatening condition. It is usually caused by polymicrobial infections or monomicrobial gram-positive organisms, mainly and . Monomicrobial gram-negative () NF is a rare form of NF, primarily reported in patients with underlying comorbidities or immunocompromised states.
View Article and Find Full Text PDFCureus
December 2024
Hand and Microsurgery Unit, Trauma and Orthopedic Department, Rashid Hospital, Dubai Health Authority, Dubai, ARE.
Soft tissue injury in open fracture of the lower extremity represents a challenging trauma that requires complex strategies to reconstruct both bony and soft tissue defects. Various options are available to cover the soft tissue defect in the lower extremities, from simple skin grafting to local fasciocutaneous and muscle flaps. However, when the injury is extensive and involves a large surface area, options for treatment of local flap coverage become limited.
View Article and Find Full Text PDFCureus
December 2024
Department of Basic Medical Sciences (Pathology), Faculty of Medicine, Jazan University, Jazan, SAU.
Basidiobolomycosis is a rare fungal infection that is triggered by the environmental saprophyte . Basidiobolomycosis usually presents as an infection beneath the skin and seldom impacts the digestive system. There is no clear clinical presentation, and the majority of initial cases are misdiagnosed.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!