AI Article Synopsis
- A new fluorescent probe called TPA-BODIPY-OH was developed, which emits light in the near-infrared (NIR) region and can effectively detect Fe and Hg ions through a hydrolysis reaction that changes its color.
- The probe exhibits three distinct emission bands (510 nm, 598 nm, and 670 nm) and has a specified stoichiometry of 1:3 for iron and 1:2 for mercury, with low detection limits for both ions (5.15 × 10⁻⁶ M for Fe and 6.81 × 10⁻⁶ M for Hg).
- In living cell imaging experiments, TPA-BODIPY-OH demonstrated its potential as a bio
Article Abstract
A novel triphenylamine-BODIPY based Schiff base fluorescent probe (TPA-BODIPY-OH) with an emission in the near-infrared (NIR) region was designed and prepared by click reaction. TPA-BODIPY-OH showed three emission bands at 510 nm, 598 nm and 670 nm, and can detect Fe and Hg ions with remarkable fluorescence enhancement in THF/HO (v/v, 1 : 1, buffered with 10 mM HEPES pH = 7.4) based on the hydrolysis reaction of the -C[double bond, length as m-dash]N bond, and naked eye detection was realized with an obvious color change. The stoichiometry between the probe and ions was deduced from a Job's plot, which is 1 : 3 for TPA-BODIPY-OH/Fe and 1 : 2 for TPA-BODIPY-OH/Hg, respectively. The dissociation constant value was found to be 1.35 × 10 M for TPA-BODIPY-OH/Fe and 2.06 × 10 M for TPA-BODIPY-OH/Hg. The low detection limit was calculated from the titration results with the values of 5.15 × 10 M for TPA-BODIPY-OH/Fe and 6.81 × 10 M for TPA-BODIPY-OH/Hg, respectively. In order to investigate the biological applications of TPA-BODIPY-OH, a living cell imaging experiment was carried out. The results demonstrate that TPA-BODIPY-OH can be successfully applied as a bioimaging agent in living cells. In addition, amino-group-functionalized silica fluorescent nanoparticles (FNPs) encapsulating the TPA-BODIPY-OH dyes were prepared and characterized by transmission electron microscopy. TPA-BODIPY-OH/SiO nanoparticles exhibit good dispersibility, and the quantum yield of FNPs at 657 nm was 42.3%.
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Article Synopsis
- A new fluorescent probe called TPA-BODIPY-OH was developed, which emits light in the near-infrared (NIR) region and can effectively detect Fe and Hg ions through a hydrolysis reaction that changes its color.
- The probe exhibits three distinct emission bands (510 nm, 598 nm, and 670 nm) and has a specified stoichiometry of 1:3 for iron and 1:2 for mercury, with low detection limits for both ions (5.15 × 10⁻⁶ M for Fe and 6.81 × 10⁻⁶ M for Hg).
- In living cell imaging experiments, TPA-BODIPY-OH demonstrated its potential as a bio
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