Design and delivery of camplatin to overcome cisplatin drug resistance.

J Mater Chem B

State Key Laboratory of Polymer Physics and Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, People's Republic of China.

Published: January 2015

Camplatin, a prodrug formed via coining camphoric anhydride and cisplatin, was delivered in biodegradable nanoparticles. This camphoric acid and cisplatin co-delivery system exhibited enhanced anticancer activity compared to cisplatin and has successfully overcome cisplatin drug resistance.

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Source
http://dx.doi.org/10.1039/c4tb01146eDOI Listing

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