Intestinal/enteric heterotopia of the vulva is an extremely rare disease with only 3 cases described in the literature. We report here an unusual case of this disease occurring in a 26-year-old patient in a context of Crohn's disease. To the best of our knowledge, such type of association has not been previously described. The potential origins of these lesions including metaplastic transformation, dysontogenetic changes, or epithelial colonic displacement/implantation are discussed.
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| http://dx.doi.org/10.1155/2020/6203826 | DOI Listing |
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Vulval Intestinal/Enteric Heterotopia in a Patient with Crohn's Disease.
Case Rep Pathol
March 2020
Department of Pathology, Erasme University Hospital/Curepath, ULB, Brussels, Belgium.
Intestinal/enteric heterotopia of the vulva is an extremely rare disease with only 3 cases described in the literature. We report here an unusual case of this disease occurring in a 26-year-old patient in a context of Crohn's disease. To the best of our knowledge, such type of association has not been previously described.
View Article and Find Full Text PDFVulval intestinal/enteric heterotopia with a 10-yr follow-up: a case report and review of the literature.
Int J Gynecol Pathol
May 2014
Division of Breast, Gynecologic & Perinatal Pathology, Institute of Pathology, University of Leipzig, Leipzig (L.-C.H.) Department of Obstetrics and Gynecology, Martin-Luther-University, Halle/Saale (U.K.B., H.-G.S, I.K.), Germany.
The occurrence of ectopic intestinal/enteric-type epithelium at the vulva is a rare entity sometimes mimicking intraepithelial neoplasia or malignant disease. Here, we report a case of an 82-yr-old woman with a long-standing (10 yr) white papillary lesion with some reddish areas at her left labium, extending into the vaginal introitus. Biopsy reports revealed colonic-type glandular epithelium with positive immunostaining against CDX-2, p53, CK 7, and CEA, whereas staining against estrogen and progesterone receptor, mammoglobin, GCDFP-15, and CK 20 was reported to be negative.
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