AI Article Synopsis
- Malignant transformation of mature cystic teratomas (MCTs) is rare, with squamous cell carcinoma being the most common type of cancer found, and there are few reports of multiple cancers developing from a single MCT.
- A specific case is presented involving a 48-year-old patient whose MCT contained both malignant papillary thyroid carcinoma and a carcinoid tumor alongside struma ovarii.
- There are currently no established guidelines for managing malignant MCTs, and this case aims to provide insights on the workup and management strategies for these uncommon transformations.
Article Abstract
Background: Malignant transformation of mature cystic teratomas (MCTs) is a rare phenomenon. The most common histology of a malignant transformation is squamous cell carcinoma, and there are limited reports of multiple malignancies arising in a single MCT. Further data are necessary to guide management of these atypical cases.
Case: We present the case of a 48-year-old with MCT containing a malignant papillary thyroid carcinoma (PTC) arising in the context of struma ovarii and a carcinoid tumour.
Conclusion: Malignant transformations of MCTs are exceedingly rare with no guidelines on management. We use this case to demonstrate an approach for the workup and management of malignantly transformed MCTs.
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Source |
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7105337 | PMC |
| http://dx.doi.org/10.3332/ecancer.2020.1009 | DOI Listing |
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