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Lysosome-targeting ratiometric fluorescent pH probes based on long-wavelength BODIPY. | LitMetric

Lysosome-targeting ratiometric fluorescent pH probes based on long-wavelength BODIPY.

J Mater Chem B

Beijing Key Laboratory for Science and Application of Functional Molecular and Crystalline Materials, Department of Chemistry, University of Science and Technology Beijing, Beijing 100083, China.

Published: July 2018

BODIPY-based probes were developed for the ratiometric fluorescence detection of pH values. They showed high sensitivity under acidic conditions via a protonation-modulated ICT mechanism and could selectively stain lysosomes, and thus could be applied for imaging and detecting abnormal pH decreases in live cells.

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Source
http://dx.doi.org/10.1039/c8tb00883cDOI Listing

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