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The impact of ciliary length on the mechanical response of osteocytes to fluid shear stress.
Nitric Oxide
December 2024
Key Laboratory for Biomechanics and Mechanobiology, Ministry of Education, Beijing Advanced Innovation Center for Biomedical Engineering, School of Biological Science and Medical Engineering, Beihang University, Beijing, 100191, China. Electronic address:
Background: Osteocytes are crucial for detecting mechanical stimuli and translating them into biochemical responses within the bone. The primary cilium, a cellular 'antenna,' plays a vital role in this process. However, there is a lack of direct correlation between cilium length changes and osteocyte mechanosensitivity changes.
View Article and Find Full Text PDFDynamic-Cross-Linked, Regulated, and Controllable Mineralization Degree and Morphology of Collagen Biomineralization.
J Funct Biomater
November 2024
Beijing International Science and Technology Cooperation Base for Intelligent Physiological Measurement and Clinical Transformation, Department of Biomedical Engineering, College of Chemistry and Life Sciences, Beijing University of Technology, Beijing 100124, China.
The cross-linking process of collagen is one of the more important ways to improve the mineralization ability of collagen. However, the regulatory effect of dynamic cross-linking on biomineralization in vitro remains unclear. Dynamic-cross-linked mineralized collagen under different cross-linking processes, according to the process of cross-linking and mineralization of natural bone, was prepared in this study.
View Article and Find Full Text PDFMild autonomous cortisol secretion leads to reduced volumetric BMD at lumbar spine in patients with primary aldosteronism.
Front Endocrinol (Lausanne)
December 2024
Department of Medicine IV, LMU University Hospital, LMU Munich, Munich, Germany.
Objectives: Glucocorticoid cosecretion is more common in primary aldosteronism (PA) than previously thought. Chronic subtle cortisol excess in patients with mild autonomous cortisol secretion (MACS) negatively affects bone health. This study aimed to evaluate the impact of MACS on bone density and turnover markers in PA patients.
View Article and Find Full Text PDFCORRECTION CRITERIA FOR THE BONE TISSUE STRUCTURE DISORDERS IN CHILDREN LIVING IN RADIOLOGICALLY CONTAMINATED TERRITORIES AFTER THE CHORNOBYL NPP ACCIDENT.
Probl Radiac Med Radiobiol
December 2024
State Institution «National Research Center of Radiation Medicine, Hematology and Oncology of the National Academy of Medical Sciences of Ukraine», 53 Yuriia Illienka Str., Kyiv, 04050, Ukraine.
Objective: To determine the structure of abnormalities of bone tissue and substantiate the management tactics inacute lymphoblastic leukemia (ALL) pediatric patients and in children with no oncohematological disorders, livingin radiologically contaminated territories (RCT).
Materials And Methods: Children (n = 220) living in RCT were the study participants i.e.
Histological Study of Skin Structures From Selected Body Areas in the Varanus komodoensis.
J Morphol
January 2025
Department of Biostructure and Animal Physiology, Division of Histology and Embryology, Faculty of Veterinary Medicine, Wrocław University of Environmental and Life Sciences, Wrocław, Poland.
The skin of the Komodo dragon (Varanus komodoensis) is covered by a form of armour formed mainly of scales, which often co-occur with osteoderms. Scales are keratinized, non-mineralized structures in the uppermost layer of the epidermis that are in contact with each other to form a system in which individual scales are isolated from each other by a softer skin fold zone. In the Varanus, the surface of the scales is flat and smooth (thoracic limb, abdomen, and tail areas), domed and smooth (head area) or domed with conical ornamentation (dorsal surface, pelvic limb-dorsal surface areas).
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