AI Article Synopsis
- * Notably, four of these compounds were identified for the first time, including a new coumarine derivative and two new furoquinolines.
- * The structures of these compounds were confirmed using NMR and mass spectrometry, and preliminary tests indicated that the stem bark extract showed promising antibacterial activity against certain human pathogens.
Article Abstract
Phytochemical examination of Drake (Rutaceae), collected in Thailand, led to the isolation of seven coumarins, four furoquinolines, two amides, and one flavonoid glycoside. Four of these compounds, one coumarine derivative named as gravelliferone A (), two furoquinoline derivatives (kokusagenin A () and B ()) and one amide, clausenalansamide H (), are reported for the first time. Compound was isolated from the root bark, compound from the stem bark and compounds and from the leaves. The molecular structures of all isolated compounds were established by means of NMR experiments combined with mass spectrometry. Preliminary tests of the lipophilic stem bark extract against various human pathogenic bacteria strains revealed promising effects against ATCC 43300.
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| http://dx.doi.org/10.1080/14786419.2020.1747455 | DOI Listing |
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