Idiopathic Granulomatous Mastitis (IGM) is an uncommon inflammatory disease of the breast, with similar presentations as breast cancer and a relatively high recurrence rate. We reviewed the demographics, clinical presentations, and treatment modalities of a large cohort of patients in Iran. Most of the patients had history of pregnancy and breastfeeding. The most common clinical finding was pain and a palpable mass, respectively. Most of the patients received medical treatment, and about half of the patients had surgery. The recurrence rate was 24.8%, and breast skin lesions were associated with a significantly higher odds of recurrence.
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http://dx.doi.org/10.1111/tbj.13822 | DOI Listing |
Breast Care (Basel)
December 2024
General Surgery Department, Şişli Etfal Training and Research Hospital, Istanbul, Turkey.
Objective: Idiopathic granulomatous mastitis (IGM) is a benign inflammatory condition predominantly affecting women of reproductive age, particularly those with a history of breastfeeding. Although the precise etiology remains unknown, treatment strategies continue to be a subject of debate. This study aimed to compare the efficacy of intralesional steroid (ILS) injections with oral steroid (OS) therapy in managing IGM.
View Article and Find Full Text PDFIr J Med Sci
December 2024
Rheumatology Department, Gülhane Training and Research Hospital, University of Health Sciences Turkey, Ankara, Turkey.
Background: Idiopathic granulomatous mastitis (IGM) is a benign and rare chronic inflammatory disease of the breast. Although there are various treatment modalities, an ideal treatment algorithm has not been defined.
Aims: We designed this study to evaluate the clinical status, duration of remission, remission rates, and treatment algorithm in patients with IGM during a 5-year follow-up period after immunosuppressive therapy.
Sarcoidosis is an immune-mediated multisystem condition of unknown etiology, characterized by non-caseating granulomatous inflammation. While it commonly affects the lungs and the reticuloendothelial system, it can affect any organ. Most of such cases involve the central nervous system, but the condition rarely presents with symptoms related to hypothalamic-pituitary dysfunction.
View Article and Find Full Text PDFPathol Int
December 2024
Department of Surgical Pathology, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Tenosynovitis with psammomatous calcification (TPC) is an extremely rare condition. It was first described as a characteristic subtype of idiopathic calcifying tenosynovitis, with only 40 cases reported to date. Here, we present a case of TPC affecting a female patient in her late teens, with no relevant medical history.
View Article and Find Full Text PDFInt J Surg Case Rep
November 2024
Associate Professor, Department of Breast Surgery, Aga Khan University Hospital, Karachi, Pakistan. Electronic address:
Introduction: Idiopathic Granulomatous Mastitis is a rare benign inflammatory disease of the breast.
Presentation Of The Case: We present a case of 45-year-old woman who was diagnosed with stage II invasive ductal carcinoma in the left breast. While receiving neoadjuvant chemotherapy, she developed idiopathic granulomatous mastitis (IGM) in the left breast after the second cycle.
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