Comparative genomics in infectious disease.

Curr Opin Microbiol

Division of Pediatric Infectious Diseases, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA; Department of Pediatrics, Perelman College of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Sackler Institute for Comparative Genomics, American Museum of Natural History, New York, NY 10024, USA. Electronic address:

Published: February 2020

With more than one million bacterial genome sequences uploaded to public databases in the last 25 years, genomics has become a powerful tool for studying bacterial biology. Here, we review recent approaches that leverage large numbers of whole genome sequences to decipher the spread and pathogenesis of bacterial infectious diseases.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10278558PMC
http://dx.doi.org/10.1016/j.mib.2020.02.009DOI Listing

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