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Durvalumab-induced Type 1 Diabetes in a Patient With Pre-existing GADA-positive Diabetes and Preserved Insulin Secretion.
JCEM Case Rep
February 2025
Department of Medical Oncology, Kameda General Hospital, Chiba 296-0041, Japan.
Predicting the onset of type 1 diabetes mellitus (T1D) in patients treated with immune checkpoint inhibitors (ICI) remains challenging. ICI-induced T1D (ICI-T1D) is a rare but serious complication that leads to complete insulin depletion. While diabetes-associated autoantibodies, such as glutamic acid decarboxylase antibodies (GADA), are typically absent in non-ICI-related fulminant T1D, they are relatively common in ICI-T1D.
View Article and Find Full Text PDFMultilocular Thymic Cyst with High F Fluorodeoxyglucose Uptake and Rheumatoid Arthritis: A Case Report.
J Clin Med
January 2025
Division of Thoracic Surgery, Policlinico Umberto I, Sapienza University of Rome, 00165 Rome, Italy.
multilocular thymic cysts are uncommon acquired cysts in the anterior mediastinum caused by incomplete thymic involution. They may be associated with autoimmune diseases, such as rheumatoid arthritis and systemic sclerosis. a 61-year-old man with a history of rheumatoid arthritis for 8 years was referred to our unit because of a multiloculated mass in the anterior mediastinum with a high F fluorodeoxyglucose uptake at PET-CT scan.
View Article and Find Full Text PDFAscaris lumbricoides a rare cause gastric perforation: a case report and brief literature review.
Front Med (Lausanne)
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Department of General Surgery, Affiliated Hospital of Hebei University, Baoding, Hebei, China.
(AL), a prevalent nematode causing ascariasis, infects millions worldwide, with a higher risk in preschool and school-aged children. Though infections are usually mild, rare and life-threatening complications like gastrointestinal perforation exist. This article documents a case involving a 61-year-old deaf-mute man who presented with a month-long history of epigastric pain accompanied by nausea, anorexia, and constipation.
View Article and Find Full Text PDFManaging Calciphylaxis: Insights from Real-World Cases at a Tertiary Academic Center.
Adv Skin Wound Care
January 2025
At University of Michigan Medical School, Ann Arbor, Michigan, United States, Kanika Kochhar, DPM, is Podiatry Fellow; and Brennen O'Dell, DPM, Garneisha Torrence, DPM, MHMS, and Alton Johnson, DPM, DABPM, FACPM, FASPS, CWSP, are Clinical Assistant Professors. Carey Spitler, MSN, NP-C, CWON, is Nurse Practitioner, University of Michigan Health, Michigan Medicine, Ann Arbor. Also at University of Michigan Medical School, Brian Schmidt, DPM, is Clinical Associate Professor.
Calciphylaxis is a rare and potentially fatal condition involving chronic, nonhealing wounds caused by microvascular calcification. There is currently no approved treatment for calciphylaxis, contributing to its devastating impacts on quality of life. In this case series, the authors highlight instances of potentially misdiagnosed calciphylaxis in a cohort of patients and emphasize the importance of accurate diagnosis through multidisciplinary management approaches.
View Article and Find Full Text PDFA 61-Year-Old Man With Weakness and Gait Dysfunction.
JAMA Neurol
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Department of Neurology, Hospital of the University of Pennsylvania, Philadelphia.
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