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Syphilitic Hepatitis: An Uncommon Manifestation of Secondary Syphilis.
Cureus
November 2024
Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles (UCLA) Health, Los Angeles, USA.
Syphilitic hepatitis is a rare manifestation of a sexually transmitted infection. Given its nonspecific presentation, it is important for clinicians to consider the diagnosis in sexually active patients presenting with elevated liver tests. In this case, a 30-year-old man presented with an itchy rash and was diagnosed with an allergic reaction.
View Article and Find Full Text PDFIsolated initial clavus-like rash: a rare presentation of secondary syphilis.
Int J STD AIDS
December 2024
Shandong First Medical University, Hospital for Skin Diseases, Jinan, China.
We report two cases of secondary syphilis with an isolated papule on the palm as the initial presentation. The clinical manifestations of secondary syphilis can be diverse, with a high rate of misdiagnosis and underdiagnosis. This article presents two patients with a purpose to alert clinicians not to forget the great imitator of syphilis for lesions of uncertain diagnosis.
View Article and Find Full Text PDFDiffuse Maculopapular Rash: An Uncommon Cutaneous Presentation of Secondary Syphilis.
Cureus
November 2024
Department of Dermatology, Cleveland Clinic Florida, Weston, USA.
Syphilis is a sexually acquired disease that can affect multiple organ systems. Secondary syphilis can cause a wide range of skin manifestations, leading to misdiagnoses. Herein, we present a patient who developed a diffuse maculopapular rash concerning for a drug reaction leading to a dermatology consult.
View Article and Find Full Text PDFNodular granulomatous secondary syphilis in a female patient: A rare presentation.
Ann Dermatol Venereol
December 2024
Dermatology Department, Edouard Herriot University Hospital, Lyon, France; Dermatology Department, Croix-Rousse University Hospital, Hospices Civils de Lyon, Lyon, France.
Seronegative and Low Seropositive Treatment-Naive Secondary Syphilis in India: A Cross Sectional Study.
Indian J Dermatol
October 2024
From the Department of Dermatology, Venereology and Leprosy, KPC Medical College and Hospital, Kolkata, West Bengal, India.
The non-treponemal tests like VDRL and RPR hold an important place in the diagnosis of syphilis. In many countries, these tests are used for screening, with positive results being subsequently confirmed by treponemal or specific tests like TPHA or FTA-ABS. Recent observations of low-titer VDRL or RPR positivity (<1:8) or negative results in patients with clinically active syphilis are becoming a cause for concern especially in the backdrop of a resurgence of the disease.
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