The application of atomic force microscopy (AFM) in ophthalmology is considered with respect of the classical anatomical division of the eye into anterior and posterior segments. The review presents the findings of published research studies that involved AFM as a method for assessing anatomical and functional condition of the structures of anterior eye segment. One significant line of research is related to the use of AFM technologies for evaluation of morphological and biomechanical characteristics of various parts of the eye lens. That topic draws interest due to the need of furthering the understanding of cataractogenesis, as well as the significance of the anatomical and functional characteristics of the lens capsule in the mechanism of accommodation and modern phaco surgery.
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