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Aberrant functional connectivity between the retrosplenial cortex and hippocampal subregions in amnestic mild cognitive impairment and Alzheimer's disease.
Brain Commun
December 2024
Department of Radiology, Aerospace Center Hospital, Beijing 100049, China.
The posterior cingulate cortex and hippocampus are the core regions involved in episodic memory, and they exhibit functional connectivity changes in the development and progression of Alzheimer's disease. Previous studies have demonstrated that the posterior cingulate cortex and hippocampus are both cytoarchitectonically heterogeneous regions. Specifically, the retrosplenial cortex, typically subsumed under the posterior cingulate cortex, is an area functionally and anatomically distinct from the posterior cingulate cortex, and the hippocampus is composed of several subregions that participate in multiple cognitive processes.
View Article and Find Full Text PDFTranscriptomics-based analysis of neurotoxic and reproductive effects in turbot (Scophthalmus maximus) after exposure to tris (2-chloroethyl) phosphate (TCEP).
BMC Genomics
January 2025
Laboratory for Marine Ecology and Environmental Science and Technology, First Institute of Oceanography, Ministry of Natural Resources, Qingdao, 266061, China.
Background: Tris (2-chloroethyl) phosphate (TCEP), a widely used flame retardant, is widespread in the environment and potentially harmful to organisms. However, the specific mechanisms of TCEP-induced neurological and reproductive toxicity in fish are largely unknown. Turbot (Scophthalmus maximus) is cultivated on a large scale, and the emergence of pollutants with endocrine disrupting effects seriously affects its economic benefits.
View Article and Find Full Text PDFRisk factors and preventive role of vaccination in adult tetanus fatality: a systematic review of reported cases (1990-2024) and meta-analysis.
Int J Infect Dis
January 2025
Koç University-Isbank Center for Infectious Diseases, Istanbul, Turkey; Department of Infectious Diseases, Koç University School of Medicine, Istanbul, Turkey. Electronic address:
Objectives: This study identifies key risk factors for fatality among adult tetanus patients and assesses the impact of vaccination status and antibody levels on disease severity and outcomes in tetanus cases. Despite widespread vaccination, fatality rates remain high due to diagnostic and management challenges.
Design/methods: A meta-analysis of 182 tetanus cases from 36 countries, published since 1990, was conducted.
Introduction: Systemic lupus erythematosus (SLE) causes widespread inflammation and damage in affected organs. Severity is determined by the type of organ systems affected and the extent of involvement. SLE occurs in childhood or adulthood and disease severity varies according to age of onset.
View Article and Find Full Text PDFThe Relationship Between Fibromyalgianess and Clinical Features, Disease Activity in Patients With Systemic Lupus Erythematosus.
Musculoskeletal Care
March 2025
Department of Rheumatology, Karamanoğlu Mehmetbey University, Karaman, Turkey.
Introduction: Fibromyalgia (FM) is a chronic syndrome characterised by widespread pain, fatigue, and symptoms such as sleep disturbances, cognitive impairment, and mood disorders. FM prevalence is notably higher among systemic lupus erythematosus (SLE) patients compared with the general population, often leading to diagnostic challenges. Misinterpreting FM as SLE activity can result in overtreatment.
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