The 2018 and 2019 guidelines from the American College of Cardiology and American Heart Association reflect the complexity of individualized cholesterol management. The documents address more detailed risk assessment, newer nonstatin cholesterol-lowering drugs, special attention to patient subgroups, and consideration of the value of therapy, all with the aim of creating personalized treatment plans for each patient. Overall, the guidelines recommend shared decision-making to meet the individual needs of each patient.
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Aim: The "2024 ACC/AHA/AACVPR/APMA/ABC/SCAI/SVM/SVN/SVS/SIR/VESS Guideline for the Management of Lower Extremity Peripheral Artery Disease" provides recommendations to guide clinicians in the treatment of patients with lower extremity peripheral artery disease across its multiple clinical presentation subsets (ie, asymptomatic, chronic symptomatic, chronic limb-threatening ischemia, and acute limb ischemia).
Methods: A comprehensive literature search was conducted from October 2020 to June 2022, encompassing studies, reviews, and other evidence conducted on human subjects that was published in English from PubMed, EMBASE, the Cochrane Library, CINHL Complete, and other selected databases relevant to this guideline. Additional relevant studies, published through May 2023 during the peer review process, were also considered by the writing committee and added to the evidence tables where appropriate.
Article Synopsis
- - The 2024 guideline focuses on managing lower extremity peripheral artery disease, providing recommendations for different patient conditions, including asymptomatic and acute limb ischemia.
- - A thorough literature review from October 2020 to June 2022 was conducted, analyzing studies published in English, with further updates considered through May 2023.
- - The updated guideline enhances the previous 2016 recommendations and introduces new strategies to ensure comprehensive care for patients suffering from peripheral artery disease.
Potential impact of blood cholesterol guidelines on statin treatment in the U.S. population using interrupted time series analysis.
BMC Cardiovasc Disord
May 2024
Institute for Health Informatics, University of Minnesota, Minneapolis, MN, USA.
Background: The 2013 ACC/AHA Guideline was a paradigm shift in lipid management and identified the four statin-benefit groups. Many have studied the guideline's potential impact, but few have investigated its potential long-term impact on MACE. Furthermore, most studies also ignored the confounding effect from the earlier release of generic atorvastatin in Dec 2011.
View Article and Find Full Text PDFClinical characteristics and statin eligibility of patients under 50 with ST-elevation myocardial infarction.
Clin Cardiol
February 2024
Division of Cardiovascular Medicine, Abbott Northwestern Hospital, Minneapolis, Minnesota, USA.
Aims: This study seeks to understand the clinical characteristics, risk factors, and statin eligibility of younger adults who present with STEMI.
Methods: We performed a retrospective analysis of a prospective cohort of STEMI patients <50 years. Baseline characteristics, medical history, prior medications, drug use, lipid profiles, cardiovascular risk factors were examined.
Comparing the association of two metabolic syndrome definitions, NCEP ATP III and IDF, with the risk of developing atherosclerotic cardiovascular disease: An analytical cross-sectional study.
Endocrinol Diabetes Metab
January 2024
Endocrinology and Metabolism Research Center, Institute of Basic and Clinical Physiology Sciences, Kerman University of Medical Sciences, Kerman, Iran.
Introduction: Atherosclerotic cardiovascular diseases (ASCVD) are significant sources of mortality and morbidity with substantial economic implications and preventive measures play key roles in this regard. Metabolic syndrome (MetS) is a common condition, and its association with ASCVD and mortality has made it clinically important. However, controversies persist regarding the best definition for MetS.
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