Citrullus colocynthis is widely distributed in the desert regions of the world. C. colocynthis has shown to improve constipation, liver diseases, jaundice, typhoid fever, diabetes and asthma in traditional use. As a kind of exterritorialy medicinal material, C. colocynthis has been used in China and introduced successfully. The main active ingredients of C. colocynthis are cucurbitacin, flavonoids, alkaloids and phenolic acids, which have been proven to have antioxidant, anti-diabetic, anti-pathogenic microorganisms and anti-cancer activities in modern pharmacological research. This paper reviews the traditional application, chemical composition and pharmacological effects of C. colocynthis, and provides reference for the in-depth study for the efficacy and mechanism of different components of C. colocynthis.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.19540/j.cnki.cjcmm.20191104.201 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Synthesis of Gold Nanoparticles Using Cucurbitacin E-Glycoside and Methyl Gallate Isolated from Citrullus colocynthis L. Fruit and Evaluation of their Antibacterial and Antibiofilm Activities.
Pharm Nanotechnol
December 2024
Central Department of Chemistry, Tribhuvan University, Kirtipur, Kathmandu 44618, Nepal.
Introduction: Metal nanoparticles have received much attention due to their unique physical dynamics, chemical reactivity, and promising biological applications. Green synthesis using natural compounds is an alternative to traditional chemical methods for the synthesis of nanoparticles.
Materials And Methods: Herein, two secondary metabolites were isolated from different fractions of methanolic extract of Citrullus colocynthis (bitter apple) Schard.
Determination of insecticidal potential of selected plant extracts against fall armyworm () larvae.
Heliyon
October 2024
Entomological Research Institute, Ayub Agricultural Research Institute, Faisalabad, Punjab, Pakistan.
Article Synopsis
- The fall armyworm is a serious agricultural pest that harms various crops, prompting a study on the effectiveness of native plant extracts as natural insecticides.
- Different concentrations of ethanolic plant extracts were tested on third-instar larvae, revealing significant mortality rates, especially at the highest concentration (400 ppm) compared to a standard chemical insecticide, Spinetoram.
- Analysis showed the plant extracts contained biologically active compounds, suggesting they could serve as eco-friendly alternatives for pest control, benefiting both the economy and the environment.
Biochemical Screening, In-vitro and In-silico Characterization of Citrullus colocynthis Fruit Extracts: A Combined Experimental and Computation Study.
Curr Pharm Biotechnol
November 2024
Department of Computer Science, Hamdard University, Islamabad, Pakistan.
Background: Several medicinal plants are identified as therapeutic agents for the world's most deadly disease cancer. A member of the "Cucurbitaceae" family of medicinal plants, Citrullus colocynthis (C. colocynthis) has various pharmacological actions.
View Article and Find Full Text PDFChromosome-level genome assembly and functional annotation of Citrullus colocynthis: unlocking genetic resources for drought-resilient crop development.
Planta
October 2024
International Center for Biosaline Agriculture, ICBA, P.O. Box 14660, Dubai, United Arab Emirates.
The chromosome-level genome assembly of Citrullus colocynthis reveals its genetic potential for enhancing drought tolerance, paving the way for innovative crop improvement strategies. This study presents the first comprehensive genome assembly and annotation of Citrullus colocynthis, a drought-tolerant wild close relative of cultivated watermelon, highlighting its potential for enhancing agricultural resilience to climate change. The study achieved a chromosome-level assembly using advanced sequencing technologies, including PacBio HiFi and Hi-C, revealing a genome size of approximately 366 Mb with low heterozygosity and substantial repetitive content.
View Article and Find Full Text PDFAdvances in Gouty Arthritis Management: Integration of Established Therapies, Emerging Treatments, and Lifestyle Interventions.
Int J Mol Sci
October 2024
Department of Orthopedics, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien 970473, Taiwan.
Article Synopsis
- * The review discusses both established and new treatment options for gouty arthritis developed from 2019 to 2024, including pharmaceutical plant additives, anti-inflammatory agents like canakinumab, and lifestyle changes.
- * Promising new approaches aim to improve uric acid metabolism and reduce inflammation, but further research is needed to confirm their effectiveness and safety before they can be widely used in clinical practice.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!