Objective: To perform criterion validation of the Key Question in Portuguese for screening at-risk alcohol use among users of Primary Healthcare services.
Method: This is a psychometric study conducted with users of a Primary Healthcare service located in the city of São Paulo, Brazil. Participants responded to the Key Question which was applied in conjunction with the Alcohol Use Disorders Identification Test-C for concurrent validation and measurement of psychometric properties.
Results: The sample consisted of 518 users. The Key Question presented 59% specificity and 99% sensitivity with respect to the Alcohol Use Disorders Identification Test-C in the general population. The accuracy was 81% in relation to this instrument. There was no influence of sociodemographic variables such as gender on the psychometric properties of the Key Question.
Conclusion: The results indicate that the Key Question in Portuguese presented satisfactory psychometric qualities and suggest that its Portuguese version is as efficient for screening at-risk alcohol use as its reference standard, which subsidizes its use in Primary Healthcare.
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http://dx.doi.org/10.1590/S1980-220X2018032503553 | DOI Listing |
ACS Nano
January 2025
Department of Chemical and Biomolecular Engineering, National University of Singapore, 4 Engineering Drive 4, Singapore 117585, Singapore.
Metal nanoclusters (NCs), owing to their atomic precision and unique molecule-like properties, have gained widespread attention for applications ranging from catalysis to bioimaging. In recent years, proteins, with their hierarchical structures and diverse functionalities, have emerged as good candidates for functionalizing metal NCs, rendering metal NC-protein conjugates with combined and even synergistically enhanced properties featured by both components. In this Perspective, we explore key questions regarding why proteins serve as complementary partners for metal NCs, the methodologies available for conjugating proteins with metal NCs, and the characterization techniques necessary to elucidate the structures and interactions within this emerging bionano system.
View Article and Find Full Text PDFKidney360
January 2025
University of Manitoba, Winnipeg, MB, Canada.
Background: Cognition is a research priority for people living with chronic kidney disease (CKD), but identification of critical research questions is lacking. This study aimed to determine which cognition-related research questions are most important to CKD stakeholders.
Methods: A modified Delphi technique with 3 survey rounds was used.
Am J Health Promot
January 2025
College of Social Work, University of South Carolina, Columbia, SC, USA.
Purpose: Artificially Intelligent (AI) chatbots have the potential to produce information to support shared prostate cancer (PrCA) decision-making. Therefore, our purpose was to evaluate and compare the accuracy, completeness, readability, and credibility of responses from standard and advanced versions of popular chatbots: ChatGPT-3.5, ChatGPT-4.
View Article and Find Full Text PDFSci Adv
January 2025
Institute of Energy, School of Earth and Space Sciences, Peking University, Beijing 100871, China.
The origins of natural hydrogen in natural gas systems of sedimentary basins and the capacity of these systems to store hydrogen remain inadequately understood, posing crucial questions for the large-scale exploration of natural hydrogen. This study reports on the natural gas composition, stable carbon and hydrogen isotopic values, and helium isotopic values of gas samples collected from the Qingshen gas deposit within volcanic rocks of the Songliao Basin. Natural hydrogen primarily originates from water radiolysis, water-rock interactions (WRI), and mantle.
View Article and Find Full Text PDFPerfusion
January 2025
Master of Science in Perfusion Program, Milwaukee School of Engineering, Milwaukee, WI, USA.
Background: In the world of academia, traditional lecturing has been the most common pedagogical approach for centuries. However, it can create an environment for students to be passive learners in the classroom. Alternatively, active learning is a pedagogical approach intended to encourage students to engage with content in manners which have been associated with improved exam performance, final course grades, clinical reasoning skills, and critical thinking skills.
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