AI Article Synopsis
- Polymyalgia rheumatica (PMR) is an inflammatory condition often seen with giant cell arteritis (GCA), making diagnosis tricky due to its vague symptoms and the presence of similar disorders.
- Advances in imaging techniques, particularly ultrasound, have helped speed up diagnosis for PMR and GCA, reducing risks like blindness.
- Glucocorticoids remain the primary treatment for both conditions, while the emergence of biological therapies like tocilizumab has expanded treatment options for GCA and minimized side effects.
Article Abstract
Polymyalgia rheumatica and Giant Cell Arteritis - Update on Diagnosis and Therapy Polymyalgia rheumatica (PMR) is an inflammatory syndrome which often co-incides with giant cell arteritis (GCA). Due to unspecific symptoms and a plethora of possible alternative diagnoses, PMR often represents a diagnostic challenge. The use of ultrasound, but also other imaging methods has improved and accelerated the time to diagnosis in PMR and GCA, so that complications such as blindness can be reduced. Glucocorticoids are still the main initial therapy for both diseases. Although further research is needed concerning prevention of and screening for long term complications for GCA, the efficacy of biologicals, namely tocilizumab, has markedly increased therapeutic options for GCA and allows for a reduction of side effects.
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| http://dx.doi.org/10.1024/1661-8157/a003444 | DOI Listing |
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