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Sex Differences in Late-life Cognition: A Psychometric Network Analysis of Well-functioning Older Adults.
Am J Geriatr Psychiatry
December 2024
Department of Gerontology, Faculty of Social Welfare & Health Sciences, University of Haifa, 199 Aba Khoushy Ave, Haifa, 3498838, Israel. Electronic address:
Objective: Unidentified sex differences in old-age cognition may emerge in psychometric networks, which look beyond mean scores into the unique cognitive structure of males and females. Accordingly, this study aims to examine cognition in well-functioning older males and females with psychometric network analysis.
Methods: The current cohort (N = 2,802) of community-dwelling adults (≥65 years) was derived from the Advanced Cognitive Training for Independent and Vital Elderly study.
SETD1B variants associated with absence seizures.
Eur J Paediatr Neurol
December 2024
Department of Pediatrics, Peking University People's Hospital, Beijing, China; Epilepsy Center, Peking University People's Hospital, Beijing, China. Electronic address:
Aim: Exploring the association between SETD1B variants and absence seizures (ASs).
Methods: We engaged a small cohort of four pediatric epilepsy patients with identified SETD1B variants and conducted a comprehensive review of 50 documented instances. Clinical profiles were meticulously compiled, and genetic screening was executed via trio-based whole-exome sequencing.
Dissociating language switching from executive control in bilinguals with MCI.
Cortex
December 2024
Memory Unit, Neurology Department, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.
Bilingual language control is a dynamic cognitive system that enables individuals to effectively manage language use and prevent interference when switching between languages. Research indicates that certain neurodegenerative conditions may influence language-switching abilities or hinder the suppression of cross-language interference. However, it remains uncertain whether neurodegeneration primarily affecting mesial temporal structures, such as Mild Cognitive Impairment (MCI), impacts lexical retrieval in dual-language naming conditions.
View Article and Find Full Text PDFThe impact of white matter lesions and subclinical cerebral ischemia on postoperative cognitive training outcomes after heart valve surgery: A randomized clinical trial.
J Neurol Sci
December 2024
Heart and Brain Research Group, Kerckhoff Heart and Thorax Center, Bad Nauheim, Germany; Department of Neurology, University Hospital Giessen and Marburg, Giessen, Germany.
Background: White matter lesions and subclinical cerebral ischemia (SCI) are described as risk factors for postoperative cognitive decline (POCD) following cardiac surgery. This report aims to investigate the effect of brain lesions on postoperative cognitive training outcomes.
Methods: In a randomized, treatment-as-usual controlled trial, elderly patients scheduled for elective heart valve surgery participated.
Building a teaching method for "clinical molecular biology testing technology" guided by the cultivation of thinking skills.
Biochem Mol Biol Educ
January 2025
College of Clinical Medicine, Hunan University of Chinese Medicine, Changsha, China.
The knowledge of "clinical molecular biology testing technology" is complex, conceptual expressions are abstract and difficult to understand, and the student's interest in learning is low. This study aimed to evaluate the effectiveness of a cyclic teaching method based on case analysis combined with an exploratory teaching method using mind mapping as an assignment. Students from the 2019 cohort of medical laboratory technology at Hunan University of Chinese Medicine served as the control group and received conventional lecture-based teaching methods.
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